Contemporary data for the global burden of sore throat and group A Streptococcus (Strep A) pharyngitis are required to understand the frequency of disease and develop value propositions for Strep A vaccines. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

This report provides an update on the contemporary global and regional policy landscapes relevant to rheumatic heart disease ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

Rosemary Sophie Jonathan Wyber La Vincente Carapetis AM R SLV JR MBChB MPH FRACGP PhD BPsych (Hons) MAppEpi PhD AM MBBS FRACP FAFPHM PhD FAHMS Senior ...

• Telethon Kids Institute
• Projects

Ruth Peter Thornton Richmond RT PC PhD MBBS MRCP(UK) FRACP Co-head, Bacterial Respiratory Infectious Disease Group (BRIDG) Head, Vaccine Trials Group ...

• Telethon Kids Institute
• Projects

Christopher Hannah Peter Peter Blyth Moore Jacoby Richmond CC HC PJ PC MBBS (Hons) DCH FRACP FRCPA PhD OAM BSc (Hons) GradDipClinEpi PhD BA (Hons) ...

• Telethon Kids Institute
• Projects
• Past projects

One third of children require repeat ventilation tube insertion (VTI) for otitis media. Disease recurrence is associated with persistent middle ear bacterial biofilms. With demonstration that Dornase alfa (a DNase) disrupts middle ear effusion biofilms ex vivo, we identified potential for this as an anti-biofilm therapy to prevent repeat VTI. First, safety and tolerability needed to be measured. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

Bhutan has reported a total of 2596 COVID-19 cases and three deaths as of September 15, 2021. With support from India, the United States, Denmark, the People’s Republic of China, Croatia and other countries, Bhutan was able to conduct two rounds of nationwide vaccination campaign. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

RHD in pregnancy (RHD-P) is associated with an increased burden of maternal and perinatal morbidity and mortality. A sequellae of rheumatic fever resulting in heart valve damage if untreated, RHD is twice as common in women. In providing an historical overview, this commentary provides context for prevention and treatment in the 21 st century. Four underlying themes inform much of the literature on RHD-P: its association with inequities; often-complex care requirements; demands for integrated care models, and a life-course approach. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

Rheumatic heart disease (RHD) persists in low-middle-income countries and in high-income countries where there are health inequities. RHD in pregnancy (RHD-P) is associated with poorer maternal and perinatal outcomes. Our study examines models of care for women with RHD-P from the perspectives of health care providers. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Uncertainties regarding inter-ethnic and preparation variability, and target exposure profiles of BPG injection are key knowledge gaps for RHD control. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021