Our data support a highly generalizable model in which enhancer transcription is the earliest event in successive waves of transcriptional change during... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

Improved opportunities for the primary prevention of ARF now exist, because of point-of-care antigen tests for Streptococcus pyogenes, and clinical decision... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

The FANTOM5 project investigates transcription initiation activities in more than 1,000 human and mouse primary cells, cell lines and tissues using CAGE. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

The MACROD2 gene is a strong positional candidate risk factor for autistic-like traits in the general population ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• December 2014

The epidemic increase in the prevalence of allergic disease, which first started in the industrialized countries in the 1960s, may have reached a peak in the... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• August 2014

The aim of this study was to explore associations between severe respiratory infections and atopy in early childhood with persisting wheeze and asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• April 2012

This methodology has significant potential to identify covert interactions between inflammatory pathways triggered by vaccination, and as such may be a... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• February 2012

Previous studies suggest that exposure to pesticides increases the risk of childhood acute lymphoblastic leukemia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• October 2011

Medulloblastoma is the most common malignant paediatric brain tumour and a leading cause of cancer-related mortality and morbidity. Existing treatment protocols are aggressive in nature resulting in significant neurological, intellectual and physical disabilities for the children undergoing treatment. Thus, there is an urgent need for improved, targeted therapies that minimize these harmful side effects. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Transcription factors known to induce the epithelial-to-mesenchymal transition (EMT) (such as ZEB1/2 [zinc finger E-box binding homeobox 1/2], SNAI1/2/3, and TWIST1/2) have been undoubtedly implicated in tumorigenesis, cancer progression, metastasis, and chemoresistance in solid tumors; however, their role in normal and malignant hematopoiesis has been underappreciated for many years. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020