Individual-based models have become important tools in the global battle against infectious diseases, yet model complexity can make calibration to biological and epidemiological data challenging. We propose using a Bayesian optimization framework employing Gaussian process or machine learning emulator functions to calibrate a complex malaria transmission simulator. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

Previous studies on the impacts of racism on adolescent development have largely overlooked Indigenous youth. We conducted a scoping review of the empirical literature on racism against Indigenous adolescents to determine the nature and scope of this research and to establish associations with developmental outcomes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• April 2022

Since 2004, malaria transmission on Bioko Island has declined significantly as a result of the scaling-up of control interventions. The aim of eliminating malaria from the Island remains elusive, however, underscoring the need to adapt control to the local context. Understanding the factors driving the risk of malaria infection is critical to inform optimal suits of interventions in this adaptive approach. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023

School attendance should therefore be a priority for all schools, and not just those with high rates of absence or low average achievement. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• March 2017

Studies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• May 2012

Microbiome Research Fellow ...

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To assess the scale of ethnic inequalities in severe maternal morbidity (SMM) rates and quantify the contribution of maternal characteristics to these disparities. This is a retrospective cohort study. A whole-of-population linked administrative data from 2002 to 2015 in Western Australia. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

This retrospective study assessed maternal and perinatal outcomes for women with rheumatic heart disease admitted to the largest tertiary obstetric hospital ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

The Australasian guidelines recommend use of the CHA2 DS2 -VA schema to stratify ischaemic stroke risk in patients with non-valvular atrial fibrillation (N-VAF) and determine risk thresholds for recommending oral anticoagulant (OAC) therapy. However, the CHA2 DS2 -VA score has not been validated in a representative Australian population cohort with N-VAF, including in Aboriginal people who are known to have a higher age-adjusted stroke risk than other Australians. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

This systematic review aimed to summarise existing literature on the impacts of armed conflicts on tuberculosis burden and treatment outcomes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024