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        Research

        Randomized controlled trial of early regular egg intake to prevent egg allergy

        We aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema. ...

        Research

        Repeat pneumococcal polysaccharide vaccine in Indigenous Australian adults is associated with decreased immune responsiveness

        These findings highlight the critical need to evaluate the efficacy of future pneumococcal vaccine programs in the Australian Indigenous populations that recommend repeated doses of 23vPPV. ...

        Research

        Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza

        These findings reinforce current recommendations for annual influenza vaccination, particularly those at greatest risk of influenza disease. ...

        Research

        Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder

        There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder have an atypical pattern of crying ...

        Research

        The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice

        This study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function. ...

        Research

        What is the evidence for managing tone in young children with, or at risk of developing, cerebral palsy: a systematic review

        To conduct a systematic review of the evidence for the management of tone in infants 0-24 months of age, with or at risk of developing cerebral palsy. ...

        Research

        Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

        We sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception. ...

        Research

        Associations of Early- and Later-Childhood Poverty with Child Cognitive Function in Indonesia: Effect Decomposition in the Presence of Exposure-Induced Mediator-Outcome Confounding

        Our analysis shows that early and late intervention to support household income have equal importance with regards to significance of impact. ...

        Research

        Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteins

        Phylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited ...

        Research

        ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

        Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes. ...

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