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        Research

        The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018

        A significant reduction in severe influenza was observed in Australian children, possibly contributed to by improved vaccine coverage and high vaccine effectiveness ...

        Research

        Simultaneous Targeting of DNA Replication and Homologous Recombination in Glioblastoma with a Polyether Ionophore

        Our findings highlight the potential of salinomycin to induce DNA lesions and inhibit homologous recombination to greatly enhance the effect of radiotherapy ...

        Research

        Analytical bias in the measurement of plasma 25-hydroxyvitamin D concentrations in infants

        To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type ...

        Research

        Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2018: the Influenza Complications Alert Network (FluCAN)

        This report summarises the epidemiology of hospitalisations with laboratory-confirmed influenza during the 2018 influenza season ...

        Research

        PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

        A novel mouse model for glioma demonstrating that the PI3K pathway is important for initiation of tumorigenesis ...

        Research

        Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion

        We found transient pDC depletion during Pneumovirus infection alone predisposed to severe bronchiolitis in early life and subsequent asthma after reinfection. ...

        Research

        The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials

        This study aimed to determine if relationships between LCI and clinical outcomes of CF lung disease differ when only two acceptable MBW trials are assessed. ...

        Research

        Potential impact of a maternal vaccine for RSV: A mathematical modelling study

        Respiratory syncytial virus is a major cause of respiratory morbidity and one of the main causes of hospitalisation in young children. ...

        Research

        Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network

        This report summarises the epidemiology of hospitalisations with laboratory-confirmed influenza during the 2015 influenza season ...

        Research

        An observational study of febrile seizures: The importance of viral infection and immunization

        Determine the frequency of detection of specific viral pathogens in children with febrile seizures ...

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