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        Research

        Repeat pneumococcal polysaccharide vaccine in Indigenous Australian adults is associated with decreased immune responsiveness

        These findings highlight the critical need to evaluate the efficacy of future pneumococcal vaccine programs in the Australian Indigenous populations that recommend repeated doses of 23vPPV. ...

        Research

        Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza

        These findings reinforce current recommendations for annual influenza vaccination, particularly those at greatest risk of influenza disease. ...

        Research

        Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder

        There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder have an atypical pattern of crying ...

        Research

        The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice

        This study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function. ...

        Research

        Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

        We sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception. ...

        Research

        Adversity and resilience amongst resettling Western Australian paediatric refugees

        Refugee children have complex backgrounds with exposure to multiple traumatic events. ...

        Research

        Associations of Early- and Later-Childhood Poverty with Child Cognitive Function in Indonesia: Effect Decomposition in the Presence of Exposure-Induced Mediator-Outcome Confounding

        Our analysis shows that early and late intervention to support household income have equal importance with regards to significance of impact. ...

        Research

        Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed Screens

        The poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput. ...

        Research

        ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

        Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes. ...

        Research

        Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteins

        Phylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited ...

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