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        Research

        Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life

        The first few days of life are characterized by rapid external and internal changes that require substantial immune system adaptations. Despite growing evidence of the impact of this period on lifelong immune health, this period remains largely uncharted.  ...

        Research

        Revaccination with Bacille Calmette-Guérin (BCG) is associated with an increased risk of abscess and lymphadenopathy

        The reported frequency and types of adverse events following initial vaccination and revaccination with Bacille Calmette-Guérin (BCG) varies worldwide. Using active surveillance in a randomised controlled trial of BCG vaccination (the BRACE trial), we determined the incidence and risk factors for the development of BCG injection site abscess and regional lymphadenopathy. ...

        Research

        Lactoferrin Expression Is Not Associated with Late-Onset Sepsis in Very Preterm Infants

        Preterm infants are at a high risk of developing late-onset sepsis (LOS). Lactoferrin is one of the most abundant endogenous antimicrobial proteins expressed in breast milk, stools, and blood, and a candidate for preventive intervention. Large clinical trials have recently investigated whether enteral supplementation with bovine lactoferrin reduces LOS. ...

        Research

        IgG Responses to Pneumococcal and Haemophilus Influenzae Protein Antigens Are Not Impaired in Children with a History of Recurrent Acute Otitis Media

        Vaccines including conserved antigens from Streptococcus pneumoniae & nontypeable Haemophilus influenzae have the potential to reduce of otitis media. ...

        News & Events

        Telethon Kids researcher awarded Research Translation Projects grant

        A new research project aims to demonstrate how influenza vaccination in children could be a highly cost-effective health care intervention in Australia. ...

        Research

        Koorlungkas yarning: Exploring the impact of OM on early language and communication skills in urban Aboriginal families

        Deborah Peter Lehmann Richmond D PC AO, MBBS, MSc MBBS MRCP(UK) FRACP Honorary Emeritus Fellow Head, Vaccine Trials Group Honorary Emeritus Fellow ...

        News & Events

        Meet END RHD CRE Researcher Dr Simone Reynolds

        Learn more about the background and motivations of END RHD CRE Research Fellow Simone Reynolds. ...

        Research

        The effectiveness of maternal pertussis vaccination for protecting Aboriginal and Torres Strait Islander infants against infection, 2012–2017: a retrospective cohort study

        To evaluate the effectiveness of maternal pertussis vaccination for preventing pertussis infections in Aboriginal and Torres Strait Islander infants under seven months of age. ...

        Research

        Estimating the excess burden of pertussis disease in Australia within the first year of life, that might have been prevented through timely vaccination

        Previous Australian studies have shown that delayed vaccination with each of the three primary doses of diphtheria-tetanus-pertussis-containing vaccines (DTP) is up to 50 % in certain subpopulations. We estimated the excess burden of pertussis that might have been prevented if (i) all primary doses and (ii) each dose was given on time. ...

        Research

        Improving Health Outcomes in the Tropical North: A Multidisciplinary Collaboration (HOT NORTH)

        Jonathan Christopher Carapetis AM Blyth JR CC AM MBBS FRACP FAFPHM PhD FAHMS MBBS (Hons) DCH FRACP FRCPA PhD Executive Director; Head, Strep A ...

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