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        Research

        Screening for rheumatic heart disease: Quality and agreement of focused cardiac ultrasound by briefly trained health workers

        After brief training, health workers with no prior experience in echocardiography can obtain adequate quality images and make a reliable assessment ...

        Research

        Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

        Free NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease ...

        Research

        The gut microbiota and inflammatory noncommunicable diseases: Associations and potentials for gut microbiota therapies

        This article discusses the relationships between gut colonization & inflammatory noncommunicable diseases, in regards to their treatment and prevention. ...

        Research

        Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage

        This study helps us understand how cancer cells are regulated by key genes and their corresponding networks to alter their fate in response to specific... ...

        Research

        The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal Carriage

        The PneuCarriage project, a large, international multi-centre study for the identification of the best pneumococcal serotyping methods for carriage studies ...

        Research

        GFP-complementation assay to detect functional CPP and protein delivery into living cells.

        Efficient cargo uptake is essential for cell-penetrating peptide (CPP) therapeutics, which deliver widely diverse cargoes by exploiting natural cell... ...

        Research

        A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinoma

        In this study, we report the case of an adolescent NMC patient presenting with severe facial pain, proptosis and visual impairment due to a mass arising from... ...

        Research

        Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

        Mature B cells, CR2/CD21 transcription proceeds from a focused TSS regulated by a non-consensus TATA box, an initiator element and downstream promoter element ...

        Research

        Expanding the clinical picture of the MECP2 Duplication syndrome

        Perinatal characteristics, early childhood development and medical co-morbidities in MECP2 Duplication syndrome ...

        Research

        Patterns of depressive symptoms and social relating behaviors differ over time from other behavioral domains for young people with Down syndrome

        People with intellectual disabilities are at a higher risk for experiencing behavioral, emotional, and psychiatric problems in comparison with the general... ...

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