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        NHMRC funding awarded to support child health research

        Telethon Kids Institute researchers have been awarded more than $10 million in research funding from the National Health and Medical Research Council (NHMRC). ...

        Research

        Pre-and Postnatal Vitamin D Status and Allergy Outcomes in Early Childhood

        The dramatic increase in the prevalence of allergic disease in recent decades reflects environmental and behavioural changes that have altered patterns of early immune development. The very early onset of allergic diseases points to the specific vulnerability of the developing immune system to environmental changes and the development of primary intervention strategies is crucial to address this unparalleled burden. ...

        Research

        A role for early oral exposure to house dust mite allergens through breast milk in IgE-mediated food allergy susceptibility

        This study highlights an unpredicted potential risk factor for the development of food allergy, that is, D pteronyssinus allergens in breast milk ...

        Research

        Whole genome and biomarker analysis of patients with recurrent glioblastoma on bevacizumab: A subset analysis of the CABARET trial.

        Whole genome sequencing of poor and exceptional survivors identified a gain in Chromosome 19 that was exclusive to the exceptional survivors ...

        Research

        Longitudinal egg-specific regulatory T- and B-cell development: Insights from primary prevention clinical trials examining the timing of egg introduction

        Egg allergy affects almost 1 in 10 Australian infants. Early egg introduction has been associated with a reduced risk in developing egg allergy; however, the immune mechanisms underlying this protection remain unclear. ...

        Research

        Antibiotic Allergy Labels in Children Are Associated with Adverse Clinical Outcomes

        This is the first study demonstrating the negative impact of antibiotic allergy labels on clinical outcomes in children ...

        Research

        Core protocol for the adaptive Platform Trial In COVID-19 Vaccine priming and BOOsting (PICOBOO)

        The need for coronavirus 2019 (COVID-19) vaccination in different age groups and populations is a subject of great uncertainty and an ongoing global debate. Critical knowledge gaps regarding COVID-19 vaccination include the duration of protection offered by different priming and booster vaccination regimens in different populations, including homologous or heterologous schedules. ...

        Research

        An Anti-VEGF-B Antibody Reduces Abnormal Tumor Vasculature and Enhances the Effects of Chemotherapy

        The vascular endothelial growth factors and their receptors are key regulators of blood vessel formation, including in tumors, where their deregulated function can promote the production of aberrant, leaky blood vessels, supporting tumor development.  ...

        Research

        Nutritional approaches for the primary prevention of allergic disease: An update

        The dramatic rise in early childhood allergic diseases indicates the specific vulnerability of the immune system to early life environmental changes. ...

        Research

        International collaboration to assess the risk of Guillain Barré Syndrome following Influenza A (H1N1) 2009 monovalent vaccines.

        The global spread of the 2009 novel pandemic influenza A (H1N1) virus led to the accelerated production and distribution of monovalent 2009 Influenza A... ...

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