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        Research

        Insulin Pump Therapy in Adolescents With Very Poor Glycemic Control During a 12-Month Cohort Trial

        We conclude that insulin pump therapy can be an effective tool to improve glycemic control in adolescents with long-standing treatment resistance ...

        Research

        Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuli

        We obtain a set of 57 candidate immediate early genes possessing promoters that consistently drive a rapid but transient increase in expression over time ...

        Research

        Inhalational versus Intravenous Induction of Anesthesia in Children with a High Risk of Perioperative Respiratory Adverse Events: A Randomized Controlled Trial

        Anesthesiologists should consider using an intravenous propofol induction technique in children who are at high risk of experiencing perioperative respiratory adverse event ...

        Research

        Comparable glycemic outcomes for pediatric type 1 diabetes patients in metropolitan and non-metropolitan regions of Western Australia: A population-based study

        This study reports similar glycemic outcomes for patients attending diabetes clinics in metropolitan and non-metropolitan areas of WA ...

        Research

        Effects of Dietary Acute Tryptophan Depletion (ATD) on NPY Serum Levels in Healthy Adult Humans Whilst Controlling for Methionine Supply-A Pilot Study

        Acute tryptophan depletion, and therefore, diminished substrate availability for brain 5-HT synthesis did not lead to significant changes in serum neuropeptide Y concentrations over time ...

        Research

        Independent and combined effects of airway remodelling and allergy on airway responsiveness

        There was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy ...

        Research

        Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP

        Our results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells ...

        Research

        Defining relevant hypoglycemia measures in children and adolescents with type 1 diabetes

        As the choices of therapies in diabetes care multiply, it is essential to standardize the approach to measuring and recording hypoglycemia risk ...

        Research

        Determinants of a dietary pattern linked with greater metabolic risk and its tracking during adolescence

        Although growing evidence suggests that dietary patterns associated with noncommunicable disease in adulthood may develop early in life. ...

        Research

        Associations between proposed local government liquor store size classifications and alcohol consumption in young adults

        Young adults' alcohol consumption appears to be impacted by liquor store density and convenience, rather than outlet size ...

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