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        Unlocking the benefit of genomics for Indigenous Australians

        Professor Alex Brown said improving access to genomic medicine for Indigenous Australians is a significant part of the Closing the Gap strategy ...

        Research

        Mitochondrial gene expression is required for platelet function and blood clotting

        Platelets are anucleate blood cells that contain mitochondria and regulate blood clotting in response to injury. Mitochondria contain their own gene expression machinery that relies on nuclear-encoded factors for the biogenesis of the oxidative phosphorylation system to produce energy required for thrombosis. ...

        Research

        In silico evolution of nucleic acid-binding proteins from a nonfunctional scaffold

        Directed evolution emulates the process of natural selection to produce proteins with improved or altered functions. These approaches have proven to be very powerful but are technically challenging and particularly time and resource intensive. To bypass these limitations, we constructed a system to perform the entire process of directed evolution in silico. ...

        Research

        Pathogenic variants in RNPC3 are associated with hypopituitarism and primary ovarian insufficiency

        We aimed to investigate the molecular basis underlying a novel phenotype including hypopituitarism associated with primary ovarian insufficiency. ...

        Research

        Living on a farm, contact with farm animals and pets, and childhood acute lymphoblastic leukemia

        These findings add additional evidence to the hypothesis that regular contact with animals in early childhood is inversely associated with childhood acute lymphoblastic leukemia ...

        Research

        Do carer’s levels of unmet needs change over time when caring for patients diagnosed with high-grade glioma and how are these needs correlated with distress?

        The aim of the current study was to determine how carer needs changed longitudinally and understand associations between unmet needs and distress. ...

        Research

        Blood micronutrients and DNA damage in children

        This is the first study to examine the associations between a range of blood micronutrient levels and DNA damage in healthy children. ...

        Research

        Parental occupational paint exposure and risk of childhood leukemia in the offspring: findings from the Childhood Leukemia International Consortium

        Using individual data from fathers of 8,185 cases and 14,210 controls, the pooled OR for paternal exposure around conception and risk of acute lymphoblastic... ...

        News & Events

        Ependymoma Awareness Day

        Ethan was not even two when he was diagnosed with a rare type of brain tumour known as an ependymoma. ...

        News & Events

        State Government boost for vital child health research

        Eight Telethon Kids Institute-led projects will benefit from a Western Australian Government boost to health research for the State’s children and young people. ...

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