Naturally acquired anti-HPV-16 antibodies were associated with a decreased risk of subsequent infection and cervical abnormalities in women >25 years ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

Our results suggest that maternal prenatal use of vitamins and folic acid reduces the risk of both ALL and AML ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• November 2014

The structures and functions of organelles in cells depend on each other but have not been systematically explored. We established stable knockout cell lines of peroxisomal, Golgi and endoplasmic reticulum genes identified in a whole-genome CRISPR knockout screen for inducers of mitochondrial biogenesis stress, showing that defects in peroxisome, Golgi and endoplasmic reticulum metabolism disrupt mitochondrial structure and function.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• January 2024

Canonical RNA processing in mammalian mitochondria is defined by tRNAs acting as recognition sites for nucleases to release flanking transcripts. The relevant factors, their structures, and mechanism are well described, but not all mitochondrial transcripts are punctuated by tRNAs, and their mode of processing has remained unsolved. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Teachers are responsible for children at school during peak ultraviolet (UV) times of the day. It is paramount that teachers have knowledge and understanding of UV to effectively protect themselves and their students. The aim of this pilot study was to investigate the effect of a short intervention on preservice teachers’ sun protective behaviours, knowledge and perceived skill to teach sun safety. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

The CART model was able to stratify surgical patients into risk groups with statistically different survival characteristics with fair to good performance ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019

Discover what's best for you, your pregnancy, baby or child at the Pregnancy Babies & Children's Expo - the must see parenting event of the year! ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2014
• August

The genetic code that specifies the identity of amino acids incorporated into proteins during protein synthesis is almost universally conserved. Mitochondrial genomes feature deviations from the standard genetic code, including the reassignment of two arginine codons to stop codons. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Programmable DNA endonucleases derived from bacterial genetic defense systems, exemplified by CRISPR-Cas9, have made it significantly easier to perform genomic modifications in living cells. However, unprogrammed, off-target modifications can have serious consequences, as they often disrupt the function or regulation of non-targeted genes and compromise the safety of therapeutic gene editing applications.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• April 2024

Developmental thymic waves of innate-like and adaptive-like γδ T cells have been described, but the current understanding of γδ T cell development is mainly limited to mouse models. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022