The aim of this study was to devise an evidence-based missing data rule for the Quality of Life Inventory-Disability (QI-Disability) questionnaire specifying how many missing items are permissible for domain and total scores to be calculated using simple imputation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

There are limited psychometric data on outcome measures for children with Developmental Epileptic Encephalopathies (DEEs), beyond measuring seizures, and no data to describe meaningful change. This study aimed to explore parent perceptions of important differences in functional abilities that would guide their participation in clinical trials. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

The COVID-19 pandemic has posed significant challenges for healthcare workers worldwide, potentially affecting their sense of coherence (SOC) and overall well-being. This study aimed to identify factors associated with different levels of SOC among healthcare workers, exploring demographic characteristics, work-related factors, changes in relationships and social habits, and the overall well-being. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• Jun 2023

These data provide proof of concept supporting the rationale for developing transplacental immune reprogramming approaches for primary disease prevention ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

High risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high versus low susceptibility to experimental asthma, induced by virus/allergen coexposure, to elucidate the mechanism(s)-of-action of the high-risk asthma immunophenotype. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

The first major national study into the cost of providing late intervention services to children and young people has called for smarter and wiser expenditure to ensure children receive vital support services at a much earlier stage. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2019
• October

What would you discover to help a child? At Telethon Kids, our researchers are committed to Autism research that makes a real difference. ...

• 1. Telethon Kids Institute
• Campaigns
• 2017
• Discover Series

Preterm birth and subsequent neonatal ventilatory treatment disrupts development of the hypoxic ventilatory response (HVR). An attenuated HVR has been identified in preterm neonates, however it is unknown whether the attenuation persists into the second year of life. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

Alexander Anthony Larcombe Kicic A A BScEnv (Hons) PhD BSc (Hons) PhD Team Leader, Respiratory Environmental Health Rothwell Family Fellow; Head, ...

• 1. Telethon Kids Institute
• Projects

Wearable motion sensors, specifically, Inertial Measurement Units, are useful tools for the assessment of orientation and movement during sleep. The DOTs platform (Xsens, Enschede, The Netherlands) has shown promise for this purpose. This pilot study aimed to assess its feasibility and validity for recording sleep biomechanics. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023