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        Research

        Seroprevalence and associated risk factors of selected zoonotic viral hemorrhagic fevers in Tanzania

        To determine the seroprevalence of selected zoonotic viral hemorrhagic fevers (VHFs) and their associated risk factors in Tanzania. ...

        Research

        Immunological mechanisms of vaccine-induced protection against COVID-19 in humans

        Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including mRNA, adenoviral-vectored, protein subunit and whole-cell inactivated virus vaccines, have now reported efficacy in phase III trials and have received emergency approval in many countries. ...

        Research

        Prospective characterisation of SARS-CoV-2 infections among children presenting to tertiary paediatric hospitals across Australia in 2020: A national cohort study

        To present Australia-wide data on paediatric COVID-19 and multisystem inflammatory syndromes to inform health service provision and vaccination prioritisation. Design Prospective, multicentre cohort study. Setting Eight tertiary paediatric hospitals across six Australian states and territories in an established research surveillance network - Paediatric Active Enhanced Disease (PAEDS). ...

        Research

        Tuberculosis related disability: a systematic review and meta-analysis

        The sustainable development goals aim to improve health for all by 2030. They incorporate ambitious goals regarding tuberculosis (TB), which may be a significant cause of disability, yet to be quantified. Therefore, we aimed to quantify the prevalence and types of TB-related disabilities. ...

        Research

        Transfluthrin eave-positioned targeted insecticide (EPTI) reduces human landing rate (HLR) of pyrethroid resistant and susceptible malaria vectors in a semi-field simulated peridomestic space

        Volatile pyrethroids (VPs) are proven to reduce human-vector contact for mosquito vectors. With increasing resistance to pyrethroids in mosquitoes, the efficacy of VPs, such as transfluthrin, may be compromised. Therefore, experiments were conducted to determine if the efficacy of transfluthrin eave-positioned targeted insecticide depends on the resistance status of malaria vectors. ...

        Research

        Clinical features and outcomes of COVID-19 and dengue co-infection: a systematic review

        Dengue is the most common arboviral disease in the tropical and sub-tropical regions of the world. Like other regions, dengue-endemic areas have faced the additional public health and socio-economic impact of the ongoing coronavirus disease 2019 (COVID-19) pandemic. ...

        Research

        Effectiveness of Palivizumab against Respiratory Syncytial Virus: Cohort and Case Series Analysis

        Palivizumab appeared effective for reducing virologically confirmed respiratory syncytial virus in this high-risk cohort ...

        Research

        The Use of Test-negative Controls to Monitor Vaccine Effectiveness: A Systematic Review of Methodology

        Our review highlights similarities and differences in the application of the test-negative design that deserve further examination ...

        Research

        S. aureus colonization in healthy Australian adults receiving an investigational S. aureus 3-antigen vaccine

        Based on descriptive analyses of this small study, S. aureus 3-antigen vaccine vaccination did not impact S. aureus acquisition or carriage ...

        Research

        Nasopharyngeal density of respiratory viruses in childhood pneumonia in a highly vaccinated setting: findings from a case-control study

        Detection of pneumonia-causing respiratory viruses in the nasopharynx of asymptomatic children has made their actual contribution to pneumonia unclear. We compared nasopharyngeal viral density between children with and without pneumonia to understand if viral density could be used to diagnose pneumonia. ...

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