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        News & Events

        Ependymoma Awareness Day

        Ethan was not even two when he was diagnosed with a rare type of brain tumour known as an ependymoma. ...

        News & Events

        Harvard Professor captivates at Annual Community Lecture

        Professor Bloom used his time to make a powerful case for the idea that 'healthier means wealthier' at the Telethon Kids Annual Community Lecture for 2017 ...

        Partnering with government to influence policy and practice

        Quick facts The Built Environments and Child Health in Wales and Australia (BEACHES) project aims to provide evidence about how built environments ...

        Research

        Unique architectural features of mammalian mitochondrial protein synthesis

        Mitochondria rely on coordinated expression of their own mitochondrial DNA (mtDNA) with that of the nuclear genome for their biogenesis. The bacterial ancestry of mitochondria has given rise to unique and idiosyncratic features of the mtDNA and its expression machinery that can be specific to different organisms. In animals, the mitochondrial protein synthesis machinery has acquired many new components and mechanisms over evolution. ...

        Research

        Illuminating mitochondrial translation through mouse models

        Mitochondria are hubs of metabolic activity with a major role in ATP conversion by oxidative phosphorylation (OXPHOS). The mammalian mitochondrial genome encodes 11 mRNAs encoding 13 OXPHOS proteins along with 2 rRNAs and 22 tRNAs, that facilitate their translation on mitoribosomes. ...

        News & Events

        Diabete$ Re$earch in Au$tralia

        It may surprise you to know that the Australian government has invested almost $300 million dollars since 2000 towards research and clinical trials for diabetes ...

        Research

        Protocol for the Care-IS Trial: a randomised controlled trial of a supportive educational intervention for carers of patients with high-grade glioma (HGG).

        This paper outlines the objectives of a randomised control trial that will be conducted to investigate primary carers of those with high-grade glioma. ...

        Research

        Vehicle refuelling, use of domestic wood heaters and the risk of childhood brain tumours: Results from an Australian case-control study

        The aetiology of childhood brain tumours (CBT) is largely unknown. ...

        Research

        The FASTK family proteins fine-tune mitochondrial RNA processing

        Transcription of the human mitochondrial genome and correct processing of the two long polycistronic transcripts are crucial for oxidative phosphorylation. According to the tRNA punctuation model, nucleolytic processing of these large precursor transcripts occurs mainly through the excision of the tRNAs that flank most rRNAs and mRNAs. ...

        Research

        Preventative therapeutic approaches for hypertrophic cardiomyopathy

        Sarcomeric gene mutations are associated with the development of hypertrophic cardiomyopathy (HCM). Current drug therapeutics for HCM patients are effective in relieving symptoms, but do not prevent or reverse disease progression. Moreover, due to heterogeneity in the clinical manifestations of the disease, patients experience variable outcomes in response to therapeutics. ...

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