BCG vaccination and revaccination are increasingly being considered for the protection of adolescents and adults against tuberculosis and, more broadly, for the off-target protective immunological effects against other infectious and noninfectious diseases. Within an international randomized controlled trial of BCG vaccination in healthcare workers (the BRACE trial), we evaluated the incidence of local and serious adverse events, as well as the impact of previous BCG vaccination on local injection site reactions (BCG revaccination). ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

Mandates provide a relatively cost-effective strategy to increase vaccinate rates. Since 2014, five Australian states have implemented No Jab No Play (NJPlay) policies that require children to be fully immunised to attend early childhood education and childcare services. In Western Australia, where this study was conducted, NJNPlay legislation was enacted in 2019.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• June 2024

A surge in invasive group A streptococcal reports in Australia has prompted Telethon Kids Institute researchers to call for a unified national public health response, with cases tipped to increase. ...

• Wesfarmers Centre of Vaccines & Infectious Diseases
• Latest news & events
• 2023

Emerging evidence suggests young children are at greater risk of COVID-19 infection than initially predicted. However, a comprehensive understanding of epidemiology of COVID-19 infection in young children under five years, the most at-risk age-group for respiratory infections, remain unclear. We conducted a systematic review and meta-analysis of epidemiological and clinical characteristics of COVID-19 infection in children under five years. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

The association between scabies and skin sores is highly significant and indicates a causal relationship ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• July 2018

increased adherence to penicillin prophylaxis is associated with reduced acute rheumatic fever recurrence and a likely reduction in mortality ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

Diarrhoeal disease is the second leading cause of death in children under 5 years globally, killing 525 000 annually. Australian Aboriginal and Torres Strait Islander (hereafter Aboriginal) children suffer a high burden of disease. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• February 2018

After brief training, health workers with no prior experience in echocardiography can obtain adequate quality images and make a reliable assessment ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

This study adds to emerging data suggesting increasing importance of iGAS in low- and middle-income settings globally. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• October 2015

These results indicate that anaphylaxis is not a major cause of adverse reactions to benzathine penicillin G ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019