Hundreds of budding female scientists from secondary schools across Western Australia will be given a glimpse into their future careers as part of the first Girls in Science Forum to be held in Perth this week. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2019
• April

The study involved screening young people to learn more about the development of long-term kidney, eye and cardiovascular complications in adolescents with T1D. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2017
• November

Telethon Kids Researchers Professor Susan Prescott and Professor Donna Cross have been appointed Fellows of the prestigious Australian Academy of Health and Med ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2015
• October

Influenza vaccination of children with medical comorbidities is critical due their increased risks for severe influenza disease. In Australia, hospitals are an avenue for influenza vaccine delivery to children with comorbidities but are not always effectively utilised. Qualitative enquiry sought to ascertainment the barriers and enablers for influenza vaccination recommendation, delivery, and recording of these children at Australian hospitals. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Canonical RNA processing in mammalian mitochondria is defined by tRNAs acting as recognition sites for nucleases to release flanking transcripts. The relevant factors, their structures, and mechanism are well described, but not all mitochondrial transcripts are punctuated by tRNAs, and their mode of processing has remained unsolved. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Vaccines have generally been developed with limited insight into their molecular impact. While systems vaccinology enables characterization of mechanisms of action, these tools have yet to be applied to infants, who are at high risk of infection and receive the most vaccines. Bacille Calmette-Guérin (BCG) protects infants against disseminated tuberculosis (TB) and TB-unrelated infections via incompletely understood mechanisms. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

Tick-borne diseases are a growing global health concern. Despite extensive studies, ill-defined tick-associated pathologies remain with unknown aetiologies. Human immunological responses after tick bite, and inter-individual variations of immune-response phenotypes, are not well characterised. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

The structures and functions of organelles in cells depend on each other but have not been systematically explored. We established stable knockout cell lines of peroxisomal, Golgi and endoplasmic reticulum genes identified in a whole-genome CRISPR knockout screen for inducers of mitochondrial biogenesis stress, showing that defects in peroxisome, Golgi and endoplasmic reticulum metabolism disrupt mitochondrial structure and function.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• January 2024

There is limited empiric evidence on the coverage of pneumococcal conjugate vaccines (PCVs) required to generate substantial indirect protection. We investigate the association between population PCV coverage and indirect protection against invasive pneumococcal disease (IPD) and pneumonia hospitalisations among undervaccinated Australian children. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

Jonathan Michael Tobias Carapetis AM Serralha Kollmann JR MS TK AM MBBS FRACP FAFPHM PhD FAHMS PhD, M.D., SFUW Executive Director; Head, Strep A ...

• Telethon Kids Institute
• Projects