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        Research

        TLR3 and RIG-I gene variants: Associations with functional effects on receptor expression and responses to measles viru

        Measles virus causes severe morbidity and mortality, despite the availability of measles vaccines. Successful defence against viral pathogens requires early... ...

        Research

        Effect of early carriage of streptococcus pneumoniae on the development of pneumococcal protein-specific cellular immune responses in infancy

        The aim of this study was to examine the relationship between nasopharyngeal pneumococcal colonization in early life and the development of T cell responses. ...

        Research

        Predominance of nontypeable haemophilus influenzae in children with otitis media

        In Australia the 7-valent pneumococcal conjugate vaccine (PCV7) is administered at 2, 4 and 6 months of age, with no booster dose. ...

        Research

        Slam and dc-sign measles receptor polymorphisms and their impact on antibody and cytokine responses to measles vaccine

        Despite the use of measles vaccine, measles virus continues to circulate and cause severe disease ...

        Research

        TLR1/2 activation during Heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T cell responses providing

        Leishmania (Viannia) parasites present particular challenges, as human and murine immune responses to infection are distinct from other Leishmania species ...

        Research

        Immediate and Longer Term Immunogenicity and Safety of a Single Dose of the Combined Haemophilus influenzae Type

        Hib-primed but MenC-naive toddlers (N = 433) were randomized to receive 1 dose of Hib-MenC-TT or separate Hib-TT and MenC-CRM197 vaccines. ...

        Research

        Innate immunity in human newborn infants: prematurity means more than immaturity

        Neonates, particularly those born prematurely, are exquisitely vulnerable to life-threatening infections. This increased susceptibility to infection... ...

        Research

        Nasopharyngeal carriage of Haemophilus haemolyticus in otitis-prone and healthy children

        Haemophilus haemolyticus is often incorrectly categorized as nontypeable Haemophilus influenzae (NTHI) upon culture. PCR analyses of 266 NTHI-like nasopharyngea ...

        Research

        Complexity of Influenza Outbreaks during the World Youth Day 2008 Mass Gathering and its Impact on Community Seasonal Influenza Activity

        How Influenza outbreaks during mass gatherings have been rarely described, and detailed virologic assessment is lacking. ...

        Research

        Comparison of the immunogenicity and reactogenicity of a prophylactic quadrivalent human papilloma Virus

        We conducted a noninferiority immunogenicity study to bridge the efficacy findings in young women to preadolescent and adolescent girls and boys... ...

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