The ORIGINS Team is studying early environments and parental physical health and genetics to uncover when and why non-communicable diseases (NCDs) develop. ...

• 1. Telethon Kids Institute
• Our research
• Early Environment
• Early Life & Life-Course Health

Although many mothers initiate breastfeeding, supplementation with human-milk substitutes (formula) during the birth hospitalization is common and has been associated with early breastfeeding cessation. Colostrum hand expressed in the last few weeks before birth, known as antenatal colostrum expression (ACE), can be used instead of human-milk substitutes. However, evidence is lacking on the efficacy of ACE on breastfeeding outcomes and in non-diabetic mothers.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

Improving maternal gut health in pregnancy and lactation is a potential strategy to improve immune and metabolic health in offspring and curtail the rising rates of inflammatory diseases linked to alterations in gut microbiota. Here, we investigate the effects of a maternal prebiotic supplement (galacto-oligosaccharides and fructo-oligosaccharides), ingested daily from <21 weeks' gestation to six months' post-partum, in a double-blinded, randomised placebo-controlled trial.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

With well-established evidence that early life conditions have a profound influence on lifespan and health-span, new interventional birth cohorts are examining ways to optimise health potential of individuals and communities. These are aimed at going beyond preventing disease, to the conditions that facilitate flourishing from an early age. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

Desiree Jackie Lisa Susan Silva Davis Gibson Prescott DS JD LG SL MBBS, FRACP, MPH, PhD BSc (Hons) BA (Hons), MPsych, PhD MBBS BMedSci PhD FRACP ...

• 1. Telethon Kids Institute
• Projects

Early onset Non-Communicable Diseases (NCDs), including obesity, allergies, and mental ill-health in childhood, present a serious and increasing threat to lifelong health and longevity. The ORIGINS Project (ORIGINS) addresses the urgent need for multidisciplinary efforts to understand the detrimental multisystem impacts of modern environments using well-curated large-scale longitudinal biological sample collections. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

This study aims to understand the experience and impact of the initial COVID-19 lock-down in young families with children aged below 4 years. Free text questions were administered to participants in the ORIGINS (Australia) and Born in Bradford (UK) cohort studies to collect qualitative information on worries, concerns and enjoyable experiences during the pandemic. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

Video technology is helping researchers learn more about the early communication style of infants with a family history of autism, ADHD or intellectual disability. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2020
• October

This letter congratulates Mulraney et al. regarding their paper on disruptive mood dysregulation disorder in children with ADHD. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• October 2015

Discover the latest community involvement opportunities from across the Institute. ...

• 1. Telethon Kids Institute
• CONNECT