Esophageal cancer is a highly aggressive malignancy with a low response to standard anti-cancer therapies. There is an unmet need to develop new therapeutic strategies to improve the clinical outcomes of current treatments. Cold atmospheric plasma (CAP) is a promising approach for cancer treatment, and has displayed anticancer efficacy in multiple preclinical models. Recent studies have shown that the efficacy of CAP is positively correlated with intracellular reactive oxygen species (ROS) levels. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

Congratulations to Indigenous genomics researcher Dr Justine Clark, who is one of two scientists nationally to receive the Australian Academy of Science’s 2024 Aboriginal and Torres Strait Islander Science Award. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2024
• February

Terrance Brittany Johns Dewdney T BD BSc, MBSc, PhD Honorary Research Associate Postdoctoral Researcher - Oncogenic Signalling Laboratory ...

• Telethon Kids Institute
• Projects

We explored familial aggregation of cancer in a population-based case-control study using genealogical record linkage and designed to overcome limitations of... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• June 2013

The asbestos and ovarian cancer relationship is not well understood because of small numbers of women exposed to asbestos, small numbers of cases... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• May 2011

Chemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens has improved response rates and increased survival in some cancers. However, most patients do not respond to treatment and immune checkpoint therapy can cause severe side effects. Therefore, there is a need for alternative immunomodulatory drugs that enhance chemotherapy. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• February 2024

This study aimed to investigate the influence factors of financial toxicity experienced by colorectal cancer patients after surgery. The results will provide deep insights for developing effective intervention strategies to address this common issue of colorectal cancer care. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• February 2024

Clinical management of breast cancer (BC) metastasis remains an unmet need as it accounts for 90% of BC-associated mortality. Although the luminal subtype, which represents >70% of BC cases, is generally associated with a favorable outcome, it is susceptible to metastatic relapse as late as 15 years after treatment discontinuation. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Newly published research from Telethon Kids Institute and The University of Western Australia has found a gel applied during surgery to treat sarcoma tumours is both safe and highly effective at preventing the cancer from growing back. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2023
• July

Cancer researchers have narrowed-down the field of immunotherapy drugs which could be used to tackle a form of childhood brain cancer. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2022
• March