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        Research

        Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow

        Injection of BM-differentiated DCs from nonchimeric mice restored the reduced immune responses of PGE2-chimeric mice. ...

        Research

        Comparing the effects of sun exposure and vitamin D supplementation on vitamin D insufficiency, and immune and cardio-metabolic function

        Adults living in the sunny Australian climate are at high risk of skin cancer, but vitamin D deficiency (defined here as a serum 25-hydroxyvitamin D... ...

        Research

        Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis

        Altered composition of gut bacteria and changes to the production of their bioactive metabolites, the short-chain fatty acids (SCFAs), have been implicated in the development of multiple sclerosis (MS). However, the immunomodulatory actions of SCFAs and intermediaries in their ability to influence MS pathogenesis are uncertain. In this study, levels of serum SCFAs were correlated with immune cell abundance and phenotype as well as with other relevant serum factors in blood samples taken at first presentation of Clinically Isolated Syndrome (CIS; an early form of MS) or MS and compared to healthy controls. There was a small but significant reduction in propionate levels in the serum of patients with CIS or MS compared with healthy controls. ...

        News & Events

        Research reveals new link between Vitamin D, lung bacteria and asthma

        A Telethon Institute for Child Health Research study has uncovered a new link between vitamin D levels and asthma. ...

        Research

        Measuring social and emotional wellbeing in aboriginal youth using strong souls: A rasch measurement approach

        Currently, there are few robustly evaluated social and emotional wellbeing (SEWB) measures available for use with Aboriginal youth in research, policy, and practice. ...

        News & Events

        The benefits of UV exposure

        For decades Australians have been told to minimise sun exposure to prevent skin cancer. ...

        Research

        The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva

        We have developed an LC-MS/MS assay that accurately measures saliva 25(OH)D3 levels, which correlated with serum levels ...

        Research

        Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin D

        UVR or sunlight exposure may be an effective means of suppressing the development of obesity and MetS, through mechanisms that are independent of vitamin D ...

        News & Events

        Government funding for innovative sun safety online tool for teens

        Telethon Kids researcher Dr Shelley Gorman has received a Healthway grant to develop an online tool to promote safe sun behaviours to teenagers. ...

        Biospecimen Service

        Contact Us Why choose BioSpecs? Since our inception in May 2020, BioSpecs has numerous agreements in place with an array of research teams from ...

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