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        71-80 of 846 results for 'early lung health'

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        BEAT CF pulmonary exacerbations core protocol for evaluating the management of pulmonary exacerbations in people with cystic fibrosis

        Cystic fibrosis (CF) is a rare, inherited, life-limiting condition predominantly affecting the lungs, for which there is no cure. The disease is characterized by recurrent pulmonary exacerbations (PEx), which are thought to drive progressive lung damage. Management of these episodes is complex and generally involves multiple interventions targeting different aspects of disease. The emergence of innovative trials and use of Bayesian statistical methods has created renewed opportunities for studying heterogeneous populations in rare diseases. ...

        Research

        Treatment with inhaled aerosolised ethanol reduces viral load and potentiates macrophage responses in an established influenza mouse model

        Treatment options for viral lung infections are currently limited. We aimed to explore the safety and efficacy of inhaled ethanol in an influenza-infection mouse model. ...

        Research

        Preterm Paediatric Inhaled Corticosteroids Intervention (PICSI)

        Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm. ...

        Research

        The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice

        This study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function. ...

        Research

        PELICAN: Prematurity’s Effects on the Lungs in Children and Adults Network

        Shannon Simpson SS BMedSci (hons), PhD Co-Head, Children's Lung Health; Senior Research Fellow 08 6319 1631 Shannon.simpson@telethonkids.org.au ...

        Research

        Air Trapping on Chest CT Is Associated with Worse Ventilation Distribution in Infants with Cystic Fibrosis

        In school-aged children with cystic fibrosis (CF) structural lung damage assessed using chest CT is associated with abnormal ventilation distribution. ...

        Research

        The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials

        This study aimed to determine if relationships between LCI and clinical outcomes of CF lung disease differ when only two acceptable MBW trials are assessed. ...

        Research

        Lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected age

        To assess whether lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected age ...

        Research

        Progressive ventilation inhomogeneity in infants with cystic fibrosis after pulmonary infection

        This study aimed to determine how pulmonary inflammation & infection impacts on ventilation distribution throughout early life in people with cystic fibrosis. ...

        Research

        Air trapping in early cystic fibrosis lung disease-Does CT tell the full story?

        Mosaic attenuation on expiratory chest computed tomography (CT) is common in early life cystic fibrosis (CF) and often referred to as "air trapping" ...

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