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        Research

        Placental Transcription Profiling in 6–23 Weeks’ Gestation Reveals Differential Transcript Usage in Early Development

        The human placenta is a rapidly developing transient organ that is key to pregnancy success. Early development of the conceptus occurs in a low oxygen environment before oxygenated maternal blood begins to flow into the placenta at ~10–12 weeks’ gestation. This process is likely to substantially affect overall placental gene expression. Transcript variability underlying gene expression has yet to be profiled. ...

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        Dr. Mary Brushe

        Senior Research Officer ...

        08 6375 6102 Email me LinkedIn
        News & Events

        2016 Events Calendar

        Find all the events the Children's Diabetes Centre have scheduled for 2016. ...

        Research

        Development of a referral pathway framework for foetal alcohol spectrum disorder in the Pilbara

        The process of referral pathway development provided a service mapping and gapping exercise to facilitate service integration ...

        People

        Sandra Van Diermen

        Community Engagement Coordinator ...

        0420 799 795 Email me
        Research

        3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk

        Genome-wide association studies (GWAS) have enabled the discovery of single nucleotide polymorphisms (SNPs) that are significantly associated with many autoimmune diseases including type 1 diabetes (T1D). However, many of the identified variants lie in non-coding regions, limiting the identification of mechanisms that contribute to autoimmune disease progression. ...

        Research

        Mapping the landscape of chromatin dynamics during naïve CD4+ T-cell activation

        T-cell activation induces context-specific gene expression programs that promote energy generation and biosynthesis, progression through the cell cycle and ultimately cell differentiation. The aim of this study was to apply the omni ATAC-seq method to characterize the landscape of chromatin changes induced by T-cell activation in mature naïve CD4+ T-cells. ...

        News & Events

        Powerful new network to ensure Indigenous Australians can benefit from genomic medicine

        A national alliance of the brightest minds in genomic science, academia, policy makers, industry and Indigenous leaders will work to break down barriers to ensure Aboriginal and Torres Strait Islander people can benefit from advances in genomic medicine if they choose. ...

        News & Events

        Port Hedland welcomes health experts from around Australia

        Port Hedland is hosting some of Australia’s most respected health researchers this week as they join forces with local health professionals to improve the health of people living in the tropical north of the country. ...

        Research

        Identifying factors contributing to shifts in children’s development on school entry in NSW over the past decade

        Alanna Neida Tess Sincovich Sechague Monroy Gregory AS NSM TG BPsych(Hons), PhD BDS, MPH BSc (Hons), PhD (Psychology) Senior Research Officer ...

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