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        Research

        Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of risk

        A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial... ...

        Research

        Trial refresh: A case for an adaptive platform trial for pulmonary exacerbations of cystic fibrosis

        This review will discuss the necessary steps required for a Bayesian adaptive platform trial to optimize treatment of pulmonary exacerbations of cystic fibrosis ...

        Research

        Improved Glycemic Outcomes With Diabetes Technology Use Independent of Socioeconomic Status in Youth With Type 1 Diabetes

        Technology use in type 1 diabetes (T1D) is impacted by socioeconomic status (SES). This analysis explored relationships between SES, glycemic outcomes, and technology use. ...

        Research

        Physical and mental health of mothers caring for a child with Rett syndrome

        This study compared the behavior profile of cases in the Australian Rett Syndrome Database (ARSD) with those in a British study using the Rett Syndrome... ...

        Research

        Whole-Cell Pertussis Vaccination and Decreased Risk of IgE-Mediated Food Allergy: A Nested Case-Control Study

        Australian infants who received whole-cell pertussis vaccines were less likely to be diagnosed with food allergy in childhood ...

        Research

        Early Life Ovalbumin Sensitization and Aerosol Challenge for the Induction of Allergic Airway Inflammation in a BALB/c Murine Model

        This protocol adapted an experimental animal model of disease for sensitization to ovalbumin during the immediate post-weaning period beginning at 21 days of age ...

        Research

        Developmental regulation of type 1 and type 3 interferon production and risk for infant infections and asthma development

        Type 1 and 3 interferon response capacity appears strongly developmentally constrained at birth ...

        Research

        A marked shift in innate and adaptive immune response in chinese immigrants living in a western environment

        There is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years ...

        Research

        Intellectual disability in children conceived using assisted reproductive technology

        The risk of intellectual disability was increased in children born after assisted reproductive technology in Western Australia from 1994 to 2002 ...

        Research

        Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations

        Our findings suggest that the proportion of degranulated basophils can also be associated with recurrent exacerbations ...

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