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        Research

        Functional validation of variants of unknown significance using CRISPR gene editing and transcriptomics: A Kleefstra syndrome case study

        There are an estimated > 400 million people living with a rare disease globally, with genetic variants the cause of approximately 80% of cases. Next Generation Sequencing (NGS) rapidly identifies genetic variants however they are often of unknown significance. ...

        Research

        Evidence that infant and early childhood developmental impairments are associated with hallucinatory experiences: Results from a large, population-based cohort study

        Cognitive and motor dysfunction are hallmark features of the psychosis continuum, and have been detected during late childhood and adolescence in youth who report psychotic experiences (PE). However, previous investigations have not explored infancy and early childhood development. ...

        Research

        Continuity of temperament subgroup classifications from infancy to toddlerhood in the context of early autism traits

        Our previous cross-sectional investigation (Chetcuti et al., 2020) showed that infants with autism traits could be divided into distinct subgroups based on temperament. This longitudinal study builds on this existing work by exploring the continuity of temperament subgroup classifications and their associations with behavioral/clinical phenotypic features from infancy to toddlerhood. ...

        Research

        Energy drink consumption is associated with anxiety in australian young adult males

        Energy drinks are predominantly targeted to young adult consumers; however, there has been limited research into their effects on psychological functioning... ...

        Research

        Living liveable? RESIDE's evaluation of the “Liveable Neighborhoods” planning policy on the health supportive behaviors and wellbeing of residents in Perth

        New suburban communities built in accordance with the “Liveable Neighbourhoods” policy have the potential to encourage health supportive behaviors ...

        Research

        The Impact of Externally Worn Diabetes Technology on Sexual Behavior and Activity, Body Image, and Anxiety in Type 1 Diabetes

        Wearable technologies impact upon sexual activity and this influences the decision to adopt the technology ...

        Research

        Disability "In-Justice": Benefits and Challenges of "Yarning" With Young People Undergoing Diagnostic Assessment for Fetal Alcohol Spectrum Disorder in Youth Detention

        We report the findings from a qualitative study that took place alongside a fetal alcohol spectrum disorder (FASD) prevalence study among detainees in Australia ...

        Research

        Does alcohol outlet density differ by area-level disadvantage in metropolitan Perth?

        This ecological study examines the distribution of liquor licences in Perth, Australia, and whether discrepancies in the distribution of retail land-uses could account for a socio-economic gradient. ...

        Research

        Dietary patterns, body mass index and inflammation: Pathways to depression and mental health problems in adolescents

        We aimed to elucidate the longitudinal relationship between dietary patterns, adiposity, inflammation and mental health in a population of adolescents. ...

        Research

        Mental health problems among 4–17-year-olds with hearing problems: results from a nationally representative study

        Clinicians caring for children and young people with hearing problems should be alert for heightened risk of specific mental health problems based on age and the nature of hearing problems. ...

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