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        Research

        Towards Improving Point-of-Care Diagnosis of Non-malaria Febrile Illness: A Metabolomics Approach

        This study demonstrates the potential use of plasma metabolites to identify causality in children with severe febrile illness in malaria-endemic settings ...

        Research

        A systems biology approach to determining the risk for development of otitis media

        Peter Ruth Elke Richmond Thornton Seppanen PC RT ES MBBS MRCP(UK) FRACP PhD BSc PhD Head, Vaccine Trials Group Co-head, Bacterial Respiratory ...

        Research

        Establishing a Western Australian Congenital and Acquired Heart Disease Database

        Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@ ...

        Research

        A retrospective population-based cohort study identifying target areas for prevention of acute lower respiratory infections in children

        Acute lower respiratory infections (ALRI) are a major cause of hospitalisation in young children ...

        Research

        Parents’ attitudes towards the No Jab No Play legislation in Western Australia: a mixed methods study

        Mandates provide a relatively cost-effective strategy to increase vaccinate rates. Since 2014, five Australian states have implemented No Jab No Play (NJPlay) policies that require children to be fully immunised to attend early childhood education and childcare services. In Western Australia, where this study was conducted, NJNPlay legislation was enacted in 2019.  ...

        Research

        Safety of BCG vaccination and revaccination in healthcare workers

        BCG vaccination and revaccination are increasingly being considered for the protection of adolescents and adults against tuberculosis and, more broadly, for the off-target protective immunological effects against other infectious and noninfectious diseases. Within an international randomized controlled trial of BCG vaccination in healthcare workers (the BRACE trial), we evaluated the incidence of local and serious adverse events, as well as the impact of previous BCG vaccination on local injection site reactions (BCG revaccination). ...

        Research

        Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis

        Emerging evidence suggests young children are at greater risk of COVID-19 infection than initially predicted. However, a comprehensive understanding of epidemiology of COVID-19 infection in young children under five years, the most at-risk age-group for respiratory infections, remain unclear. We conducted a systematic review and meta-analysis of epidemiological and clinical characteristics of COVID-19 infection in children under five years. ...

        Research

        Severe adverse events following benzathine penicillin G injection for rheumatic heart disease prophylaxis: cardiac compromise more likely than anaphylaxis

        These results indicate that anaphylaxis is not a major cause of adverse reactions to benzathine penicillin G ...

        Research

        How many doses make a difference? An analysis of secondary prevention of rheumatic fever and rheumatic heart disease

        increased adherence to penicillin prophylaxis is associated with reduced acute rheumatic fever recurrence and a likely reduction in mortality ...

        Research

        Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study

        The association between scabies and skin sores is highly significant and indicates a causal relationship ...

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