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        Research

        Oral prednisolone in preschool children with virus-associated wheeze: A prospective, randomised, double-blind, placebo-controlled trial

        Preschool children often have episodes of virus-associated wheeze and assessing efficacy of corticosteroids for paediatric wheeze exacerbations is inconcludsive ...

        Research

        A retrospective population-based cohort study identifying target areas for prevention of acute lower respiratory infections in children

        Acute lower respiratory infections (ALRI) are a major cause of hospitalisation in young children ...

        Research

        Enhancing Protection against Influenza and COVID-19 for pregnant women and medically at risk children: EPIC Study

        Christopher Blyth CC MBBS (Hons) DCH FRACP FRCPA PhD Director, Wesfarmers Centre of Vaccines and Infectious Diseases; Co-Head, Infectious Diseases ...

        Research

        Evaluation of Children's Centres in South Australia

        Yasmin Alanna Harman-Smith Sincovich YHS AS BA, BHlthSc(Hons), PhD BPsych(Hons), PhD Head, Early Years Systems Evidence; Head, Tenders Support Unit ...

        News & Events

        New meningococcal strains bring increased risk in WA

        A new study has confirmed the changing pattern of meningococcal disease in Western Australia. ...

        Research

        Parental awareness and attitudes towards prevention of respiratory syncytial virus in infants and young children in Australia

        To assess parental awareness of respiratory syncytial virus (RSV) and the level of acceptance of future RSV prevention strategies. A cross-sectional online survey was implemented targeting "future" and "current" parents of children aged ≤5 years in Australia. ...

        Research

        Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease

        Genomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays. ...

        Research

        Urinary tract infections in children: building a causal model-based decision support tool for diagnosis with domain knowledge and prospective data

        Diagnosing urinary tract infections (UTIs) in children in the emergency department (ED) is challenging due to the variable clinical presentations and difficulties in obtaining a urine sample free from contamination. ...

        Research

        Chronic health conditions, mental health and the school: A narrative review

        School-based social risk processes in the lives of young people with chronic health conditions are likely to contribute to risk of psychological problems ...

        Research

        Narrowband UVB phototherapy reduces TNF production by B-cell subsets stimulated via TLR7 from individuals with early multiple sclerosis

        At the end of a 60-day course of narrowband UVB phototherapy, administered to individuals with early multiple sclerosis, there were changes in the relative proportions of circulating B-cell subsets. This study investigated phototherapy-associated changes to cytokine responses of B cells when exposed to a TLR7 ligand. ...

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