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        Research

        A diagnostic test for acute rheumatic fever (pilot study)

        Jonathan Tim Carapetis AM Barnett JR TB AM MBBS FRACP FAFPHM PhD FAHMS PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Head of ...

        RHD Endgame Strategy

        RHD Endgame Strategy: Evidence Briefs 5 Priority Areas for Implementation Priority Action Areas Acknowledgements Increasing access to swimming pools ...

        Research

        First Nations populations' perceptions, knowledge, attitudes, beliefs, and myths about prevention and bereavement in stillbirth: a mixed methods systematic review protocol

        The objective of this review is to investigate First Nations populations' perceptions, knowledge, attitudes, beliefs, and myths about stillbirth. ...

        Research

        Effectiveness of 13-valent pneumococcal conjugate vaccine against hypoxic pneumonia and hospitalisation in Eastern Highlands Province, Papua New Guinea: An observational cohort study

        Pneumonia is a leading cause of childhood mortality with Streptococcus pneumoniae a major contributor. Pneumococcal conjugate vaccines (PCVs) have been introduced into immunisation programs in many low- to middle-income countries yet there is a paucity of data evaluating the effectiveness in these settings. We assess the effectiveness of 13-valent PCV against hypoxic pneumonia, hospitalisation and other clinical endpoints in children <5 years living in Eastern Highlands Province, Papua New Guinea). ...

        Research

        Sleep Disordered Breathing and Recurrent Tonsillitis Are Associated With Polymicrobial Bacterial Biofilm Infections Suggesting a Role for Anti-Biofilm Therapies

        The underlying pathogenesis of pediatric obstructive sleep disordered breathing (SDB) and recurrent tonsillitis (RT) are poorly understood but need to be elucidated to develop less invasive treatment and prevention strategies. ...

        Research

        Understanding the aetiology and resolution of chronic otitis media from animal and human studies

        This Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition ...

        Research

        Pneumococcal responses are similar in Papua New Guinean children aged 3-5 years vaccinated in infancy with pneumococcal polysaccharide vaccine with or without prior pneumococcal conjugate vaccine, or without pneumococcal vaccination

        We studied in a non-randomized follow-up trial the persistence of pneumococcal immunity in children, 3-5 years of age, in community controls of a similar age. ...

        Research

        Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease

        Chronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function ...

        Research

        Self-harm: Prevalence estimates from the second Australian Child and Adolescent Survey of Mental Health and Wellbeing

        The demonstrated higher risks in young people for continued harm or possible death support the need for ongoing initiatives to reduce self-harm ...

        Research

        Impact of adolescent peer aggression on later educational and employment outcomes in an Australian cohort

        This study used prospective birth cohort data to analyse the relationship between peer aggression at 14 years of age and educational and employment outcomes... ...

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