There is no data exclusively on the relationship between health-related quality-of-life (HRQOL) and lung disease severity in early school-aged children with cystic fibrosis (CF). Using data from the Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) we assessed the relationships between HRQOL, lung function and structure. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Australian energy drink users tend to have heavier alcohol consumption patterns be a cigarette smoker and use illicit drugs relative to non-users. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• September 2013

The PLAYCE study will empirically investigate the relative and cumulative influence of the day care, and home environment on preschoolers’ physical activity ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• December 2016

Systematic comparison of recovered cell types and their transcriptional profiles across the workflows has highlighted protocol-specific biase ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Immunotherapies have revolutionized cancer treatment. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some cancers. However, the majority of treated patients do not respond. Understanding immune mechanisms that underlie responsiveness to ICT will help identify predictive biomarkers of response and develop treatments to convert non-responding patients to responding ones. ICT primarily acts at the level of adaptive immunity. The specificity of adaptive immune cells, such as T and B cells, is determined by antigen-specific receptors. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Measurement of lung volumes across the life course is critical to the diagnosis and management of lung disease. The aim of the study was to use the Global Lung Function Initiative methodology to develop all-age multi-ethnic reference equations for lung volume indices determined using body plethysmography and gas dilution techniques. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

To investigate epigenomic indices of diabetic kidney disease (DKD) susceptibility among high-risk populations with type 2 diabetes mellitus.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• September 2023

Interest in how the school built environment impacts bullying behaviour has gained momentum in recent years. While numerous studies have identified locations within schools where bullying frequently occurs, few studies have investigated the potential conceptual pathways linking school locations to bullying behaviour. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

This review explores computational strategies to yield biological insight into the processes involved in the immunotherapeutic response ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

Investigate the world's largest and most powerful supermarkets' publically available CSR commitments to determine their potential impact on public health ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018