This review explores computational strategies to yield biological insight into the processes involved in the immunotherapeutic response ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

T cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy with inferior outcome compared with that of B cell ALL. Here, we show that Runt-related transcription factor 2 (RUNX2) was upregulated in high-risk T-ALL with KMT2A rearrangements (KMT2A-R) or an immature immunophenotype. In KMT2A-R cells, we identified RUNX2 as a direct target of the KMT2A chimeras, where it reciprocally bound the KMT2A promoter, establishing a regulatory feed-forward mechanism. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

To assess the relative effectiveness of topical versus systemic antibiotics for people with chronic suppurative otitis media ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

Population-based primary prevention of ARF through sore throat management may be effective in well-resourced settings like New Zealand ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• October 2018

Chromosome 6q26-27 is linked to susceptibility to visceral leishmaniasis (VL) in Brazil and Sudan. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• August 2012

Mailing list Be Inspired Join thousands of active subscribers and hear about the brave kids, dedicated researchers, and world-leading science at ...

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• 2017

Browse the published work of the Centre's researchers ...

• Rio Tinto Children's Diabetes Centre
• Our research

This paper describes a mathematical model used to predict when an epidemic of respiratory syncytial virus (RSV) will occur so that preventive measures, such... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

Respiratory syncytial virus (RSV) remains a leading cause of mortality and morbidity worldwide. RSV seasonality was disrupted by COVID-19-associated nonpharmaceutical interventions (NPIs). We review RSV seasonality, molecular epidemiology, clinical manifestations, and community awareness to inform future prevention strategies.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

Contact us If you'd like to get in touch, please contact us by phone or email. Phone: 0400 450 240 Email: vtg@telethonkids.org.au Respiratory ...

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• 2017 Update for the Vaccine Trials Group