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        Research

        Assessing the protective effect of influenza vaccine against laboratory confirmed influenza in hospitalised children aged 6-59 months

        Influenza vaccine was offered to all children aged 6-59 months resident in Western Australia in 2008, and we wished to evaluate the effectiveness of this immunisation programme. ...

        Research

        Detection of the rapid emergency of the H274 mutation associated with oseltamivir-resistance

        In 2009 a new swine-origin influenza virus A/H1N1 (A/H1N1 09) emerged, causing the century's first pandemic. ...

        Research

        1,25-dihydroxyvitamin D3 enhances the ability of transferred CD4+ CD25+ cells to modulate T helper type 2-driven asthmatic responses

        The severity of allergic diseases may be modified by vitamin D. However, the immune pathways modulated by the active form of vitamin D, 1,25-dihydroxyvitamin D. ...

        Research

        Characteristics of non-Aboriginal and Aboriginal children and families with substantiated child maltreatment

        To investigate specific child and parental factors associated with increased vulnerability to substantiated child maltreatment. ...

        Research

        Interpretation of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine is adversely affected by methodological inaccuracies when using a commercial ELISA

        The DNA lesion 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), a urinary marker of oxidative stress, is produced from reactions of reactive oxygen ...

        Research

        Interactions between innate and adaptive immunity in asthma pathogenesis: new perspectives from studies on acute exacerbations

        Atopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review. ...

        Research

        Antimicrobial susceptibility of Moraxella catarrhalis isolated from children in Kalgoorlie-Boulder

        To investigate antimicrobial susceptibility of Moraxella catarrhalis isolated from a cohort of children being followed in a study of the natural history of OM ...

        Research

        Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia

        Pre-clinical models that effectively recapitulate human disease are critical for expanding our knowledge of cancer biology and drug resistance mechanisms. ...

        Research

        Apolipoprotein E genotype is associated with serum C-reactive protein but not abdominal aortic aneurysm

        We assessed the association between ApoE genotype with AAA presence and growth, and serum C-reactive protein (CRP). ...

        Research

        The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheeze

        A recently proposed method for classifying preschool wheeze is to describe it as either episodic (viral) wheeze or multiple trigger wheeze. ...

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