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        Research

        Airway IRF7hi versus IRF7lo molecular response patterns determine clinical phenotypes in children with acute wheezing

        We employed a systems biology approach to delineate upper airway gene network patterns underlying asthma exacerbation phenotypes in children. ...

        Research

        Parent-reported health-related quality of life of children with Down syndrome: A descriptive study

        To describe health-related quality of life of Australian children and adolescents with Down syndrome and compare it with norm-referenced data. ...

        Research

        CDKL5 variants: Improving our understanding of a rare neurologic disorder

        Providing new insights into the interpretation of genetic variants in a rare neurologi disorder, in the contexts of population sequencing data. ...

        Research

        Toxoplasma gondii infection is associated with mitochondrial dysfunction in-vitro

        Our results show perturbation of host mitochondrial function following T. gondii infection that likely impacts on pathogenesis of disease. ...

        Research

        Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells

        Apically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces. ...

        Research

        Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells

        This study assessed an alternative approach, using a small scale halide assay that can be adapted for a personalized high throughput setting to analyze CFTR function of pAEC. ...

        Research

        Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder

        ASD's are complex, pervasive and heterogeneous neurodevelopmental conditions with varying conditions, trajectories, significant male bias and unknown etiology. ...

        Research

        Associations between cardiovascular disease and its risk factors with hearing loss—A cross-sectional analysis

        We investigate the relationship between hearing loss and cardiovascular disease risk factors. ...

        Research

        What are the position and power of supermarkets in the Australian food system, and the implications for public health? A systematic scoping review

        This review synthesized the literature that describes the position and power of supermarkets in the Australian system, and the implications for public health. ...

        Research

        Common and differential factors associated with abstinence and poly drug use among Australian adolescents

        The aim of this study was to identify factors associated with compliance with recommendation for zero use of tobacco, alcohol and cannabis, and their use. ...

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