Antimicrobial resistance poses a significant threat to modern healthcare as it limits treatment options for bacterial infections, particularly impacting those with chronic conditions such as cystic fibrosis (CF). Viscous mucus accumulation in the lungs of individuals genetically predisposed to CF leads to recurrent bacterial infections, necessitating prolonged antimicrobial chemotherapy. Pseudomonas aeruginosa infections are the predominant driver of CF lung disease, and airway isolates are frequently resistant to multiple antimicrobials. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

This study aimed to identify the quality of life domains important for individuals with CDKL5 deficiency disorder ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019

This study demonstrates novel intrinsic differences in tight junctions gene and protein expression between airway epithelial cells of children with and without asthma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Our data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• April 2018

The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

These data highlight that early life levels of vitamin D are an important consideration for maternal behavioural adaptations as well as offspring neuropsychiatry ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Quality of life of young people with Down syndrome was most negatively associated with burden of medical conditions, but also with lack of friendships ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

A biologically active vaccine may produce a low measured vaccine efficacy under a range of epidemiological, vaccine-related and logistical conditions ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

To assess the effects of systemic antibiotics for people with chronic suppurative otitis media. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

To assess the effects of topical antiseptics for people with chronic suppurative otitis media ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018