Children typically experience more mild symptoms of Coronavirus Disease 2019 (COVID-19) when compared to adults. There is a strong body of evidence that children are also less susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection with the ancestral viral isolate. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

We observed an association between Type III DNA methyltransferase presence and Otitis Media-associated middle ear isolates ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

Recently, "Technical standards for respiratory oscillometry" was published, which reviewed the physiological basis of oscillometric measures and detailed the technical factors related to equipment and test performance, quality assurance and reporting of results. Here we present a review of the clinical significance and applications of oscillometry. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

Stephen Tobias Stick Kollmann SM TK MB BChir PhD MRCP FRACP PhD, M.D., SFUW Head, P4 Respiratory Health for Kids Honorary Research Associate 08 6319 ...

• 1. Telethon Kids Institute
• Projects

Deborah Chris Tamara Lehmann Brennan-Jones Veselinovic D C TV AO, MBBS, MSc PhD MClinAud Honorary Emeritus Fellow Head, Ear Health Clinical Research ...

• 1. Telethon Kids Institute
• Projects

Comparison of Influenza C viruses detected from Australian clinical samples with Influenza C viruses detected in other parts of the world in recent years ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• November 2016

Both tumour suppressive and oncogenic functions have been reported for dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Herein, we performed a detailed investigation to delineate the role of DYRK1A in glioblastoma. Our phosphoproteomic and mechanistic studies show that DYRK1A induces degradation of cyclin B by phosphorylating CDC23, which is necessary for the function of the anaphase-promoting complex, a ubiquitin ligase that degrades mitotic proteins. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Early changes in cell morphology upon treatments are a strong indication that the inhibitor is directly targeting tubulin ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

Perth respiratory researchers have discovered that giving an immune booster to mothers during pregnancy could increase their newborns’ resistance to severe and life-threatening respiratory viral infections. ...

• Wal-yan Respiratory Research Centre
• News & events
• 2021
• September

Nontypeable Haemophilus influenzae (NTHi) is the most common bacterial otopathogen associated with otitis media (OM). NTHi persists in biofilms within the middle ears of children with chronic and recurrent OM. Australian Aboriginal children suffer exceptionally high rates of chronic and recurrent OM compared to non-Aboriginal children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• April 2022