Why are we doing AusVaxSafety? Like any other medication, vaccines can have side effects which are usually mild and short-lasting and do not need ...

• Wesfarmers Centre of Vaccines & Infectious Diseases
• Our research
• Vaccine Trials Group
• Current studies

Maternal educational attainment (MEA) shapes offspring health through multiple potential pathways. Differential DNA methylation may provide a mechanistic understanding of these long-term associations. We aimed to quantify the associations of MEA with offspring DNA methylation levels at birth, in childhood and in adolescence. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

To investigate the relationships between cardiorespiratory fitness and adiposity among young children, and their influence on a comprehensive cardiovascular ris ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• October 2010

Gene transfer to a donor cornea ex vivo can modulate corneal graft failure in experimental animal models. We compared a lentiviral vector (LV) carrying... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• May 2010

A new report has been released into the impact of genomic medicine and technologies on global public health. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2010
• November

Research on adults has identified an immigrant health advantage, known as the 'immigrant health paradox', by which migrants exhibit better health outcomes than natives. Is this health advantage transferred from parents to children in the form of higher birth weight relative to children of natives? ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023

Fetal exposure to maternal smoking during pregnancy is associated with the development of noncommunicable diseases in the offspring. Maternal smoking may induce such long-term effects through persistent changes in the DNA methylome, which therefore hold the potential to be used as a biomarker of this early life exposure. With declining costs for measuring DNA methylation, we aimed to develop a DNA methylation score that can be used on adolescent DNA methylation data and thereby generate a score for in utero cigarette smoke exposure. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• September 2020

Epigenetics links perinatal influences with later obesity. We identifed differentially methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity measures and examined whether these were associated with hsCRP, adipokines, and early life environmental factors. Genome-wide DNA methylation from 1192 Raine Study participants at 17 years, identified 29 dmCpGs associated with body mass index, 10 with waist circumference and 9 with subcutaneous fat thickness. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

This cohort study provides new evidence of a disparity between the proportion of the population with rare diseases and their combined health-system costs ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017

In 2010, the Australasian Paediatric Endocrinology Group formed a national Children's Diabetes Network that represented clinical teams managing over 95% of... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• April 2013