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        Research

        Clinical practice guidelines for paediatric X-linked hypophosphataemia in the era of burosumab

        X-linked hypophosphataemia (XLH), the most common inherited form of rickets, is caused by a PHEX gene mutation that leads to excessive serum levels of fibroblast growth factor 23 (FGF23). This leads to clinical manifestations such as rickets, osteomalacia, pain, lower limb deformity and overall diminished quality of life. ...

        Research

        A systematic review of the importance of milk TGF-β on immunological outcomes in the infant and young child

        Cytokines in milk like transforming growth factor-beta (TGF-beta) have been shown to induce oral tolerance in experimental animal studies ...

        Research

        In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in mice

        All alterations to lung mechanics following in utero arsenic exposure were recovered by adulthood. ...

        Research

        Investment in child and adolescent health and development: key messages from Disease Control Priorities, 3rd Edition

        The realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence. ...

        News & Events

        Colostrum’s critical role in fighting undernutrition(2)

        In celebration of World Breastfeeding Week (August 1-7), we're thrilled to share our latest research that's revolutionising our understanding of breast milk and supporting breastfeeding mothers. ...

        Research

        Umbilical venous blood flow and its measurement in the human fetus

        In this review, we evaluate the published methodologies to describe a noninvasive technique for the quantitative assessment of umbilical venous blood flow in... ...

        Research

        Relationship between environmental exposures in children and adult lung disease: the case for outdoor exposures

        There is a growing understanding that chronic respiratory diseases in adults have their origins in early life ...

        Research

        Home-based multidisciplinary interventions on skin adverse reactions in EGFR-TKI-treated patients with lung cancer: a protocol for a randomised controlled trial

        Here, we provide a feasible, well-designed protocol of a randomised controlled trial for the assessment of the effects of a home-based multidisciplinary intervention on the severity of skin adverse drug reactions and health-related indicators in patients with non-small cell lung cancer (NSCLC) under epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy. ...

        Research

        Changes in referral patterns for weight in association with the preschool Raising Healthy Kids target

        The 'Raising Healthy Kids (RHK) health target ' recommended that children identified as having obesity [body mass index (BMI) >/=98th centile] through growth screening at the B4 School Check (B4SC) be offered referral for subsequent assessment and intervention. ...

        Research

        Validation of a model for optimal birth weight: A prospective study using serial ultrasounds

        The aim of this study was to validate a model for optimal birth weight derived from neonatal records, and to test the assumption that preterm births may be... ...

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