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        81-90 of 115 results for 'alexander larcombe'

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        Research

        Influence of gestational age on dead space and alveolar ventilation in preterm infants ventilated with volume guarantee

        Ventilated preterm infant lungs are vulnerable to overdistension and underinflation. ...

        Research

        Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells

        Apically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces. ...

        Research

        Route of exposure alters inflammation and lung function responses to diesel exhaust

        In this study, we compared the physiological consequences of short-term exposure to diesel exhaust via inhalation to those due to exposure to the same diesel... ...

        News & Events

        Pregnant women urged to avoid e-cigarettes

        Women who are pregnant or who think they could be have been urged to avoid using e-cigarettes, due to lack of evidence about their safety. ...

        News & Events

        Study shows e-cigarettes can harm lungs

        A study led by researchers at the Telethon Kids Institute has shown that electronic cigarettes can cause lung damage. ...

        Research

        Using Systems Biology to understand asthma exacerbations and develop better treatments

        Alexander Anthony Deborah Emma Jean-Francois Pat Larcombe Kicic Strickland de Jong Lauzon-Joset Holt A A DH EdJ JFLJ PG BScEnv (Hons) PhD BSc (Hons) ...

        News & Events

        ‘Nicotine-free’ e-juice samples found to contain nicotine and harmful chemicals

        Six out of ten ‘nicotine-free’ e-cigarette liquids analysed by Telethon Kids Institute researchers contained nicotine as well as an acutely toxic chemical typically found in pesticides and disinfectants. ...

        Research

        Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation

        These data provide proof of concept supporting the rationale for developing transplacental immune reprogramming approaches for primary disease prevention ...

        Research

        IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming

        High risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high versus low susceptibility to experimental asthma, induced by virus/allergen coexposure, to elucidate the mechanism(s)-of-action of the high-risk asthma immunophenotype. ...

        Research

        Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability

        HRV-1B infection directly alters human airway epithelial TJ expression leading to increased epithelial permeability potentially via antiviral response of IL-15 ...

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