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        Research

        Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia

        Pre-clinical models that effectively recapitulate human disease are critical for expanding our knowledge of cancer biology and drug resistance mechanisms. ...

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        Sosthenes Ketende

        Honorary Team Member ...

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        Kevin Runions

        Honorary Research Associate ...

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        Research

        Mapping tuberculosis prevalence in Ethiopia using geospatial meta-analysis\

        Reliable and detailed data on the prevalence of tuberculosis (TB) with sub-national estimates are scarce in Ethiopia. We address this knowledge gap by spatially predicting the national, sub-national and local prevalence of TB, and identifying drivers of TB prevalence across the country. ...

        Research

        Using Linked Population Data to Investigate the Impact of Intimate Partner Violence on Children's Outcomes

        Melissa Rebecca O'Donnell Glauert M RA BPsych (Hons), MPsych, GradDip Ed, PhD BPsych (Hons) PhD Honorary Research Associate Honorary Research ...

        Research

        School Readiness of Children Exposed to Family and Domestic Violence

        Children have a universal right to live free from exposure to family and domestic violence (FDV). Children exposed to FDV can experience long-term effects on their physical and psychological health and their social competencies including social, emotional, and cognitive skills and behaviours that underpin successful social adaptation and academic achievement. The aim of this study was to investigate if children exposed to FDV were more likely to be vulnerable on school readiness measures compared to those children who were not exposed. ...

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        Asthma and allergies in a cohort of adolescents conceived with ART

        Research question: Are asthma and allergies more common in adolescents conceived with assisted reproductive technologies (ART) compared with adolescents conceived without? ...

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        Remission of peanut allergy is associated with rewiring of allergen-driven T helper 2-related gene networks

        The immunological changes underpinning acquisition of remission (also called sustained unresponsiveness) following food immunotherapy remain poorly defined. Limited access to effective therapies and biosamples from treatment responders has prevented progress. Probiotic peanut oral immunotherapy is highly effective at inducing remission, providing an opportunity to investigate immune changes. ...

        Research

        Treatment Outcomes among Pregnant Patients with Multidrug-Resistant Tuberculosis: A Systematic Review and Meta-analysis

        The management of multidrug-resistant tuberculosis (MDR-TB) during pregnancy is challenging, yet no systematic synthesis of evidence has accurately measured treatment outcomes. ...

        Research

        Biological sex estimation using ancient DNA in Classic Maya contexts: some findings from Naachtun (Guatemala)

        Recent advances in paleogenomics have opened up new prospects for the study of ancient burial customs and social structures. In this note, we report on the first results of a program now under way in a small residential compound in Naachtun, Guatemala. ...

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