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        Research

        Pertussis immunisation in infancy and atopic outcomes: A protocol for a population-based cohort study using linked administrative data

        The burden of IgE-mediated food allergy in Australian born children is reported to be among the highest globally. This illness shares risk factors and frequently coexists with asthma, one of the most common noncommunicable diseases of childhood. ...

        Research

        Whole-cell pertussis vaccine in early infancy for the prevention of allergy

        This is a protocol for a Cochrane Review (intervention). The objectives were to assess the efficacy and safety of whole‐cell pertussis (wP) vaccinations in comparison to acellular pertussis (aP) vaccinations in early infancy for the prevention of atopic diseases in children. ...

        Research

        Blocking Notch3 Signaling Abolishes MUC5AC Production in Airway Epithelial Cells from Asthmatics

        We demonstrate that NOTCH3 is a regulator of MUC5AC production ...

        Research

        Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma

        Airway interleukin-33 is associated with type-2 cytokines in naturally occurring asthma exacerbations in adults ...

        Research

        Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observed

        We aim to provide our view of where we are and where we need to go as a community of clinicians and researchers who tackle the public health problem of asthma. ...

        Research

        A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

        To introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation. ...

        Research

        Airway epithelial repair in health and disease: Orchestrator or simply a player?

        This review attempts to highlight migration-specific and cell-extracellular matrix (ECM) aspects of repair used by epithelial cells ...

        Research

        Environmental microbial exposure and protection against asthma

        This article looks at the clinical implications of the research into microbial exposure & protection against asthma. ...

        Research

        Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants

        The purpose of this article is to highlight emerging evidence for existing allergy prevention guidelines regarding potential benefits of supporting early... ...

        Research

        Der p 11 is a major allergen for house dust mite-allergic patients suffering from atopic dermatitis

        House dust mites (HDMs) belong to the most potent indoor allergen sources worldwide and are associated with allergic manifestations in the respiratory tract. ...

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