Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• June 2010

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André Timo Anthony Kathryn Peter Sam Alex Bep Thomas Schultz Lassmann Kicic Ramsey Richmond Buckberry Brown Uink Iosifidis AS T A KR PC SB AB BU TI ...

• Telethon Kids Institute
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Tess Yasmin Neida Gregory Harman-Smith Sechague Monroy TG YHS NSM BSc (Hons), PhD (Psychology) BA, BHlthSc(Hons), PhD BDS, MPH Senior Research ...

• Telethon Kids Institute
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• Brain and Behaviour
• Population Health Program
• Early Years Systems Evidence

One of the most traumatic injuries a child can experience is a severe burn. Despite improvements in medical treatments which have led to better physical outcomes and reduced mortality rates for paediatric burns patients, the psychological impact associated with experiencing such a traumatic injury has mostly been overlooked. This is concerning given the high incidence of psychopathology amongst paediatric burn survivors.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• February 2024

The aim of this study was to determine the unique and shared contributions of various positive psychology constructs (gratitude, optimism, hope, self-compassion, self-efficacy, and emotion regulation) to wellbeing and distress outcomes in young people living with a diverse range of chronic health conditions.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• November 2023

A standardised framework for selecting outcomes for evaluation in trials has been proposed by the Core Outcome Measures in Effectiveness Trials working group. However, this method does not specify how to ensure that the outcomes that are selected are causally related to the disease and the health intervention being studied. Causal network diagrams may help researchers identify outcomes that are both clinically meaningful and likely to be causally dependent on the intervention, and endpoints that are, in turn, causally dependent on those outcomes. ...

• Telethon Kids Institute
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• Reports and Findings
• 2021
• October 2021

Laboratory models provide an important tool in helping to understand the cellular and molecular drivers of respiratory disease. Many animal models exist that model the neonatal outcomes of preterm birth. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

While chemotherapy remains the first-line treatment for many cancers, it is still unclear what distinguishes responders from non-responders. Here, we characterize the chemotherapy-responsive tumor microenvironment in mice, using RNA sequencing on tumors before and after cyclophosphamide, and compare the gene expression profiles of responders with progressors. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Medulloblastoma is the most common childhood brain cancer. Mainstay treatments of radiation and chemotherapy have not changed in decades and new treatment approaches are crucial for the improvement of clinical outcomes. To date, immunotherapies for medulloblastoma have been unsuccessful, and studies investigating the immune microenvironment of the disease and the impact of current therapies are limited. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022