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        Research

        Airway management in the paediatric difficult intubation registry: a propensity score matched analysis of outcomes over time

        The Paediatric Difficult Intubation Collaborative identified multiple attempts and persistence with direct laryngoscopy as risk factors for complications in children with difficult tracheal intubations and subsequently engaged in initiatives to reduce repeated attempts and persistence with direct laryngoscopy in children. We hypothesised these efforts would lead to fewer attempts, fewer direct laryngoscopy attempts and decrease complications. ...

        Research

        Mosaic Darier disease flaring following allogeneic stem cell transplant

        Bernadette Ricciardo BR MBBS (hon) DCH FACD PhD Candidate Bernadette.Ricciardo@telethonkids.org.au PhD Candidate Dr Bernadette Ricciardo is a PhD ...

        Research

        Gut microbiota and metabolomics profiles in patients with chronic stable angina and acute coronary syndrome

        Cardiovascular disease is the leading cause of death worldwide. The gut microbiota and its associated metabolites may be involved in the development and progression of CVD, although the mechanisms and impact on clinical outcomes are not fully understood. This study investigated the gut microbiome profile and associated metabolites in patients with chronic stable angina and acute coronary syndrome compared with healthy controls. ...

        Research

        Outcomes of latent rheumatic heart disease: External validation of a simplified score in patients with and without secondary prophylaxis

        Secondary antibiotic prophylaxis reduces progression of latent rheumatic heart disease (RHD) but not all children benefit. Improved risk stratification could refine recommendations following positive screening. We aimed to evaluate the performance of a previously developed echocardiographic risk score to predict mid-term outcomes among children with latent RHD.  ...

        Research

        In safe hands: child health data storage, linkage and consent for use

        While there is potential for societal benefit from linkage and integration of large datasets, there are gaps in our understanding of the implications for children and young people, and limited inclusion of their views within this discourse. We aimed to understand the views and expectations of children, young people and their parents/caregivers in Aotearoa New Zealand regarding child health data storage, linkage and consent for use. ...

        Research

        Australian children's physical activity and screen time while in grandparental care

        The objective of this study was to explore Australian children's engagement in physical activity and screen time while being cared for by their grandparents. ...

        Research

        Behavioural and neuropsychological outcomes in children exposed in utero to maternal labour epidural analgesia

        Recent studies report conflicting results regarding the relationship between labour epidural analgesia (LEA) in mothers and neurodevelopmental disorders in their offspring. We evaluated behavioural and neuropsychological test scores in children of mothers who used LEA. ...

        Research

        Capacity building to address antimicrobial resistance in remote Australia: The inaugural HOT NORTH Antimicrobial Academy

        Rates of antimicrobial resistance (AMR) for some pathogens in Australia are considerably higher in rural and remote compared to urban regions. The inaugural Hot North Antimicrobial Academy was a 9-month educational programme aimed to build workforce knowledge and capacity in antimicrobial use, audit, stewardship, surveillance and drug resistance in remote primary health care.  ...

        Research

        The respiratory health effects of acute in vivo diesel and biodiesel exhaust in a mouse model

        Biodiesel, a renewable diesel fuel that can be created from almost any natural fat or oil, is promoted as a greener and healthier alternative to commercial mineral diesel without the supporting experimental data to back these claims. The aim of this research was to assess the health effects of acute exposure to two types of biodiesel exhaust, or mineral diesel exhaust or air as a control in mice. ...

        Research

        Thoracic Society of Australia and New Zealand position statement: The safe clinical use of sputum induction for bio-sampling of the lower airways in children and adults

        Sputum induction is widely used in clinical settings for collection of biological samples from the lower airways. However, in recent years sputum induction has been associated with serious adverse events and even death. This position statement was commissioned by the Thoracic Society of Australia and New Zealand to address major adverse events of two deaths associated with sputum induction that have occurred in Australia in 2021, and outlines best practice for the safe use of sputum induction.  ...

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