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        Research

        Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas

        The outcome for children with high-grade gliomas (HGG) remains dismal, with a 2-year survival rate of only 10% to 30%. ...

        Research

        Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea

        Our objectives were to describe the incidence rate of motor vehicle crashes (MVCs) in patients with obstructive sleep apnea (OSA) and to investigate MVC risk... ...

        Research

        The Differential Influence of Contextual Risks on Psychosocial Functioning and Participation of Australian Aboriginal Youth

        Methodological issues and implications for interventions to support young Aboriginal people's adaptation are discussed. ...

        Research

        Chest computed tomography: a validated surrogate endpoint of cystic fibrosis lung disease?

        Clinical trials for the treatment of cystic fibrosis (CF) lung disease are important to test and optimise new therapeutic interventions. ...

        Research

        Common variation contributes to the genetic architecture of social communication traits

        Andrew Whitehouse Watch and listen to Andrew AJ PhD Angela Wright Bennett Professor of Autism Research at Telethon Kids Institute; Director, ...

        Research

        A "bottom-up" approach to aetiological research in autism spectrum disorders

        Autism spectrum disorders (ASD) are currently diagnosed in the presence of impairments in social interaction and communication, and a restricted range of... ...

        Research

        DSM-IV-TR and DSM-5 eating disorders in adolescents: Prevalence, stability, and psychosocial correlates in a population-based sample

        Eating disorder prevalence rates were significantly greater when using DSM-5 than DSM- IV-TR criteria, at all time points for females and at age 17 only... ...

        Research

        Hypomethylation of the CTGF gene locus is a common feature of paediatric pre-B acute lymphoblastic leukaemia

        We identified consistent hypomethylation of the CTGF locus in primary pre-B ALL specimens regardless of CTGF expression. ...

        Research

        Evaluating a community-based early childhood education and development program in Indonesia: study protocol for a pragmatic cluster randomized controlled trial

        The aim of the trial is to evaluate a community-based early education and development program launched by the Government of Indonesia. ...

        Research

        Long-term outcome of insulin pump therapy in children with type 1 diabetes assessed in a large population-based case-control study

        We determined the impact of insulin pump therapy on long-term glycaemic control, BMI, rate of severe hypoglycaemia and diabetic ketoacidosis (DKA) in children. ...

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