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        Research

        Rurality as a predictor of perinatal mental health and well-being in an Australian cohort

        Perinatal emotional well-being is more than the presence or absence of depressive and anxiety disorders; it encompasses a wide range of factors that contribute to emotional well-being. ...

        Research

        A systematic review of the biological, social, and environmental determinants of intellectual disability in children and adolescents

        This systematic review aimed to identify the most important social, environmental, biological, and/or genetic risk factors for intellectual disability. ...

        Research

        Mind the distance: experiences of non-face-to-face child and youth mental health services during COVID-19 social distancing restrictions in Western Australia

        Following the outbreak of COVID-19, social distancing restrictions limited access to face-to-face mental health services in Western Australia (WA), necessitating a rapid transition to non-face-to-face alternatives, including telehealth. The current study investigated barriers and facilitators to telehealth access and engagement, and preferences for child and youth mental health service delivery during and beyond COVID-19. ...

        Research

        Skin health situational analysis to inform skin disease control programs for the Kimberley

        Asha Bowen AC BA MBBS DCH FRACP PhD GAICD OAM Head, Healthy Skin and ARF Prevention Head, Healthy Skin and Arf Prevention Areas of expertise: Skin ...

        Research

        Dental care experiences and clinical phenotypes in children on the autism spectrum

        Children diagnosed with autism spectrum disorder may be at higher likelihood of experiencing poorer oral health and difficulties accessing dental health care. However, identifying which children on the autism spectrum may be more vulnerable to experiencing dental care difficulties is still unknown. ...

        Research

        Pseudomonas aeruginosa modulates neutrophil granule exocytosis in an in vitro model of airway infection

        A population of neutrophils recruited into cystic fibrosis (CF) airways is associated with proteolytic lung damage, exhibiting high expression of primary granule exocytosis marker CD63 and reduced phagocytic receptor CD16. Causative factors for this population are unknown, limiting intervention. Here we present a laboratory model to characterize responses of differentiated airway epithelium and neutrophils following respiratory infection. ...

        Research

        Maternal influenza vaccination and child mortality: Longitudinal, population-based linked cohort study

        Influenza vaccination is recommended to protect mothers and their infants from influenza. Few studies have evaluated the association between maternal influenza vaccination and child mortality. We aimed to evaluate the association between in utero exposure to seasonal inactivated influenza vaccine (IIV) and mortality among young children. ...

        Research

        Universal child health and early education service use from birth through Kindergarten and developmental vulnerability in the Preparatory Year (age 5 years) in Tasmania, Australia

        This study investigated patterns of universal health and education service use from birth through Kindergarten (age 4 years) and estimated associations between cumulative risk and service use patterns, and between service use patterns and children's developmental vulnerability in the Preparatory Year (age 5 years). ...

        Research

        “We don’t want you to come in and make a decision for us”: Traversing cultural authority and responsive regulation in Australian child protection systems

        The Ngulluk Koolunga Ngulluk Koort (Our Children Our Heart) project conducted extensive Elder and community consultation to develop principles and practice recommendations for child protection governance in Western Australia. We explore these principles and practice recommendations and highlight the need for culturally safe community consultation and governance with a focus on repairing damage incurred by the Aboriginal and Torres Strait Islander community from past child protection policies. ...

        Research

        Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major

        The macrophage infectivity potentiator (Mip) protein, which belongs to the immunophilin superfamily, is a peptidyl-prolyl cis/trans isomerase (PPIase) enzyme. Mip has been shown to be important for virulence in a wide range of pathogenic microorganisms. ...

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