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        Research

        Machine learning and clinical epigenetics: a review of challenges for diagnosis and classification

        We now have a growing number of epigenetic alterations in disease, and this offers a chance to increase sensitivity and specificity of future diagnostics and therapies ...

        Research

        The Wittenoom legacy

        The legacy of Wittenoom has extended beyond the mine and the town, and is still evident more than 50 years after the closure of the mine ...

        Research

        The Brain Basis of Comorbidity in Neurodevelopmental Disorders

        This review discusses early brain development and the etiological factors that may give rise to atypical developmental trajectories, along with neuroimaging insights ...

        Research

        Immunogenicity and Immune Memory after a Pneumococcal Polysaccharide Vaccine Booster in a High-Risk Population Primed with Pneumococcal Conjugate Vaccine

        PPV is immunogenic in 9-month-old children at high risk of pneumococcal infections and does not affect the capacity to produce protective immune responses ...

        Research

        Trial refresh: A case for an adaptive platform trial for pulmonary exacerbations of cystic fibrosis

        This review will discuss the necessary steps required for a Bayesian adaptive platform trial to optimize treatment of pulmonary exacerbations of cystic fibrosis ...

        Research

        Narrative Medicine Meets Planetary Health: Mindsets Matter in the Anthropocene

        We argue that the principles and practice of narrative medicine can be applied on a larger scale, one with planetary health in mind ...

        Research

        Children and adolescents with type 1 diabetes in Australasia: An online survey of model of care, workforce and outcomes

        Survey of the model of care and workforce that manages children and adolescents with type 1 diabetes in Australasia along with glycaemic outcomes ...

        Research

        Prediction modelling using routine clinical parameters to stratify survival in Malignant Pleural Mesothelioma patients undergoing cytoreductive surgery

        The CART model was able to stratify surgical patients into risk groups with statistically different survival characteristics with fair to good performance ...

        Research

        The effect of aquatic high-intensity interval training on aerobic performance, strength and body composition in a non-athletic population

        In a non-athletic population, aquatic-high-intensity interval training was safe and may have improved aerobic performance and lower limb strength ...

        Research

        Higher non-processed red meat consumption is associated with a reduced risk of central nervous system demyelination

        We found no statistically significant association between processed red meat density and risk of a first clinical diagnosis of central nervous system demyelination ...

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