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        Research

        A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence

        Recurrences frequently occur following surgical removal of primary tumors. In many cancers, adjuvant therapies have limited efficacy. Surgery provides access to the tumor microenvironment, creating an opportunity for local therapy, in particular immunotherapy, which can induce local and systemic anti-cancer effects. ...

        Research

        Skin Health in Northern Australia

        Achieving healthy skin requires the prevention of infectious diseases that affect the skin. Prevention activities range from environmental health improvements to address inequities in living situations, through to community-wide treatment programs to reduce transmission and improve skin health. ...

        Research

        The ventilatory response to hypoxia is blunted in some preterm infants during the second year of life

        Preterm birth and subsequent neonatal ventilatory treatment disrupts development of the hypoxic ventilatory response (HVR). An attenuated HVR has been identified in preterm neonates, however it is unknown whether the attenuation persists into the second year of life. ...

        Research

        Goal motives and mental contrasting with implementation intentions facilitate strategic goal persistence and disengagement

        In three experiments, we examine the role of motives underlying goal pursuit and the metacognitive strategy of mental contrasting with implementation intentions (MCII) to predict the strategic use of self-regulation responses (persistence, disengagement, and reengagement) when faced with attainable, unattainable, or multiple goals. ...

        Research

        Increased levels of solar radiation are associated with reduced type-2 diabetes prevalence: A cross-sectional study of Australian postcodes

        Type-2 diabetes is a leading cause of death and disability. Emerging evidence suggests that ultraviolet radiation or sun exposure may limit its development. We used freely available online datasets to evaluate the associations between solar radiation and type-2 diabetes prevalence across Australia. ...

        Research

        Frankenstein Cas9: engineering improved gene editing systems

        The discovery of CRISPR-Cas9 and its widespread use has revolutionised and propelled research in biological sciences. ...

        Research

        Celebrating the lived experience of socio-economic disadvantage in the public health workforce

        Joelie Mandzufas JM BCom BHSc GCHELT Project Coordinator Joelie.mandzufas@telethonkids.org.au PhD Student Joelie Mandzufas is a PhD student with the ...

        Research

        The health-related quality of life of lung cancer patients with EGFR-TKI-related skin adverse drug reactions and its relationship with coping style and self-management

        The status and associated factors of the health-related quality of life of non-small-cell lung cancer patients under targeted anti-cancer therapy have not been investigated. Self-management and coping style have been proven to be closely related to patients’ health-related quality of life. ...

        Research

        Probiotic supplementation in neonates with congenital gastrointestinal surgical conditions: a pilot randomised controlled trial

        To evaluate whether probiotic supplementation attenuates gut-dysbiosis in neonates with congenital gastrointestinal surgical conditions. ...

        Research

        Molecular Mechanisms and Applications of N-Acyl Homoserine Lactone-Mediated Quorum Sensing in Bacteria

        Microbial biodiversity includes biotic and abiotic components that support all life forms by adapting to environmental conditions. Climate change, pollution, human activity, and natural calamities affect microbial biodiversity. ...

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