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        1-10 of 13 results for 'melissa penny'

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        Melissa Penny

        Professor Fiona Stanley Chair in Child Health Research ...

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        Research

        Severe outcomes of malaria in children under time-varying exposure

        In malaria epidemiology, interpolation frameworks based on available observations are critical for policy decisions and interpreting disease burden. Updating our understanding of the empirical evidence across different populations, settings, and timeframes is crucial to improving inference for supporting public health. ...

        Research

        Seasonal malaria chemoprevention and the spread of Plasmodium falciparum quintuple-mutant parasites resistant to sulfadoxine–pyrimethamine: a modelling study

        Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine prevents millions of clinical malaria cases in children younger than 5 years in Africa's Sahel region. However, Plasmodium falciparum parasites partially resistant to sulfadoxine-pyrimethamine (with quintuple mutations) potentially threaten the protective effectiveness of SMC. We evaluated the spread of quintuple-mutant parasites and the clinical consequences.  ...

        Research

        Efficacy thresholds and target populations for antiviral COVID-19 treatments to save lives and costs: a modelling study

        In 2023 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared endemic, yet hospital admissions have persisted and risen within populations at high and moderate risk of developing severe disease, which include those of older age, and those with co-morbidities. Antiviral treatments, currently only available for high-risk individuals, play an important role in preventing severe disease and hospitalisation within this subpopulation. ...

        Research

        Intervention effect of targeted workplace closures may be approximated by single-layered networks in an individual-based model of COVID-19 control

        Individual-based models of infectious disease dynamics commonly use network structures to represent human interactions. Network structures can vary in complexity, from single-layered with homogeneous mixing to multi-layered with clustering and layer-specific contact weights. Here we assessed policy-relevant consequences of network choice by simulating different network structures within an established individual-based model of SARS-CoV-2 dynamics. ...

        News & Events

        Leading disease modeller appointed inaugural Fiona Stanley Chair of Child Health Research

        Telethon Kids Institute and The University of Western Australia are proud to announce the appointment of the inaugural Fiona Stanley Chair of Child Health Research, Professor Melissa Penny. ...

        Research

        Design and selection of drug properties to increase the public health impact of next-generation seasonal malaria chemoprevention: a modelling study

        Seasonal malaria chemoprevention (SMC) is recommended for disease control in settings with moderate to high Plasmodium falciparum transmission and currently depends on the administration of sulfadoxine-pyrimethamine plus amodiaquine.  ...

        Intervention and Infectious Disease Modelling

        The Intervention and Infectious Disease Modelling group informs development and implementation of drugs, medical treatments and non-medical interventions to effectively tackle disease. They build mathematical models of diseases, designed to take into account the complex constellation of interactions between pathogens, humans, diseases, the environment and entire healthcare systems. ...

        Research

        Ngulluk Moort, Ngulluk Boodja, Ngulluk Wirin (Our Family, Our Country, Our Spirit) Out-of-Home Care Study

        Brad Carrington Raewyn Carol Melissa Farrant Shepherd Mutch Michie O'Donnell Photos BM CCJ RM C M BSc (Hons), PhD PhD MBChB., DipRACOG., Cert.HPRT, ...

        Current donors

        $1m - $9,999,999 $500k - $999,999 $100k - $499,999 $25k - $99,999 $10k - $24,999 $1 - $9,999 BHP Channel 7 Telethon Child Cancer Research Foundation ...

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