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        Start smart: a program for healthy mobile technology use by young children

        Investigators: Donna Cross External collaborators: Leon Straker (Curtin University of Technology), Erin Howie (Curtin University of Technology), Susan Danby (Queensland University of Technology) The project aims to design, test, refine and ...

        Research

        Indigenous Capacity Building Grant (ICBG)

        This was a five year grant from the National Health and Medical Research Council (NHMRC) awarded in 2004 after an application spearheaded by Perth's Telethon Institute for Child Health Research, along with Curtin University of Technology, the ...

        Research

        Prenatal alcohol and tobacco use and the risk of depression in offspring at age of 17 years: findings from the Raine Study

        Prenatal alcohol and tobacco exposures have been associated with adverse mental health consequences in offspring. The objective of this study was to test the associations between maternal prenatal alcohol and tobacco exposures and depressive symptoms in the offspring, adjusting for a wide range of potential confounders. ...

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        Chemical analysis of new and “aged” e-liquids: Development of a rapid toxicological screening approach

        Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

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        It is more “unbalanced” than you think

        Sébastien Malinge SM PhD Laboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior Research Fellow (UWA), University Associate (Curtin) Sebastien.malinge@telethonkids.org.au Laboratory ...

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        Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort study

        There is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments. ...

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        Comparative effectiveness of interventions for preventing tuberculosis: systematic review and network meta-analysis of interventional studies

        Tuberculosis (TB) is the leading infectious cause of death globally. Several preventive measures are employed to prevent TB, yet there is a paucity of evidence on the effectiveness of these interventions. Therefore, this study aimed to identify the most effective interventions for reducing TB incidence. ...

        Research

        Lung function changes in children exposed to mine fire smoke in infancy

        Chronic, low-intensity air pollution exposure has been consistently associated with reduced lung function throughout childhood. However, there is limited research regarding the implications of acute, high-intensity air pollution exposure. We aimed to determine whether there were any associations between early life exposure to such an episode and lung growth trajectories. ...

        Research

        Variants associated with HHIP expression have sexdifferential effects on lung function

        Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sexdifferential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females. ...

        Research

        Development of a Symptom-Based Tool for Screening of Children at High Risk of Preschool Asthma

        Despite advances in asthma therapeutics, the burden remains highest in preschool children; therefore, it is critical to identify primary care tools that distinguish preschool children at high risk for burdensome disease for further evaluation. ...

        Research

        Prevalence of tuberculosis infection among contacts of drug-resistant tuberculosis patients: A systematic review and meta-analysis

        Contact investigations with drug-susceptible tuberculosis (DS-TB) patients have demonstrated a high prevalence of tuberculosis infection (TBI). However, the prevalence of TBI among individuals in close contact with drug-resistant tuberculosis (DR-TB) patients is poorly understood. This systematic review and meta-analysis aimed to determine the prevalence of TBI among household and non-household contacts of DR-TB patients. ...

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        Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data

        Towards the goal of malaria elimination on Hispaniola, the National Malaria Control Program of Haiti and its international partner organisations are conducting a campaign of interventions targeted to high-risk communities prioritised through evidence-based planning. Here we present a key piece of this planning: an up-to-date, fine-scale endemicity map and seasonality profile for Haiti informed by monthly case counts. ...

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