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        A Phase 3, randomized, double-blind trial to evaluate the safety and immunogenicity of a 20-valent pneumococcal conjugate vaccine given as a series of 2 infant doses and 1 toddler dose in healthy infants (NeXXstep)

        Jennifer Peter Kent Richmond J PC RN MBBS MRCP(UK) FRACP Clinical Research Manager Head, Vaccine Trials Group Jennifer.Kent@telethonkids.org.au Clinical Research Manager Head, Vaccine Trials Group Jennifer completed her Diploma of Nursing in 1986 at ...

        Research

        OPTIMUM: OPTimising IMmunisation Using Mixed schedules

        Pat Peter Susan Tom Jennifer Holt Richmond Prescott Snelling Kent PG PC SL T J PhD, DSc, FRCPath, FRCPI, FAA MBBS MRCP(UK) FRACP MBBS BMedSci PhD FRACP BMBS DTMH GDipClinEpid PhD FRACP RN Emeritus Honorary Researcher Head, Vaccine Trials Group ...

        Research

        Pneumococcal responses are similar in Papua New Guinean children aged 3-5 years vaccinated in infancy with pneumococcal polysaccharide vaccine with or without prior pneumococcal conjugate vaccine, or without pneumococcal vaccination

        We studied in a non-randomized follow-up trial the persistence of pneumococcal immunity in children, 3-5 years of age, in community controls of a similar age. ...

        Research

        Using record linkage to validate notification and laboratory data for a more accurate assessment of notifiable infectious diseases

        Studies investigating pathogen-specific infectious disease would benefit from using multiple data sources. ...

        Research

        ‘Is it like one of those infectious kind of things?’ The importance of educating young people about HPV and HPV vaccination at school

        Greater knowledge and understanding of National Human Papillomavirus vaccination appeared to promote positive attitudes towards vaccination ...

        Research

        Otitis-prone children produce functional antibodies to pneumolysin and pneumococcal polysaccharides

        The production of functional antipneumococcal antibodies in otitisprone children demonstrates that they respond to the current pneumococcal conjugate vaccine (PCV)and are likely to respond to pneumolysin-based vaccines as effectively as healthy children. ...

        Research

        No evidence for impaired humoral immunity to pneumococcal proteins in Australian Aboriginal children with otitis media

        Conserved vaccine candidate proteins from S.pneumoniae induce serum and salivary antibody responses in Aboriginal and non-Aboriginal children with history of OM ...

        Research

        Safety and immunogenicity of a booster dose of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults: A randomized phase 1 study

        Immune responses after the initial vaccination persisted for the 12 months studied, with little additional response after the booster dose at 6 months ...

        Research

        Antibiotic duration and timing of the switch from intravenous to oral route for bacterial infections in children: systematic review and guidelines

        Systematic review of antibiotic duration and timing of intravenous to oral switch for paediatric infectious diseases and evidence-graded recommendations ...

        Research

        Influenza vaccine effectiveness and uptake in children at risk of severe disease

        Participation in the preschool influenza vaccination program remains low with parents unconvinced of the benefits and safety of influenza vaccine ...

        Research

        Predominant bacteria detected from the middle ear fluid of children experiencing otitis media: A systematic review

        Globally, S. pneumoniae and H. influenzae remain the predominant otopathogens associated with OM as identified through bacterial culture ...

        Research

        Ahead of consensus: A paediatric antifungal prophylaxis census

        To contextualise the ‘Australian & New Zealand Antifungal Consensus Guidelines, 2014, researchers surveyed current routine primary antifungal prophylaxis. ...

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