With the deadly and highly transmissible SARS-CoV-2 virus causing the COVID-19 pandemic, there is global concern about the danger of contaminating healthcare workers (HCW), particularly during airway management of infected patients. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

We aimed to examine genetic and nongenetic determinants of change in serum 25-hydroxyvitamin D (25(OH)D) after supplementation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

Bubble CPAP may be used in infants with suspected or confirmed COVID-19. Electrostatic filters may reduce cross infection. This study aims to determine if including a filter in the bubble CPAP circuit impacts stability of pressure delivery. A new electrostatic filter was placed before (pre) or after (post) the bubble CPAP generator, or with no filter (control) in an in vitro study. Pressure was recorded at the nasal interface for 18 h (6 L/min; 7 cm H2O) on 3 occasions for each configuration. Filter failure was defined as pressure >9 cm H2O for 60 continuous minutes. The filter was weighed before and after each experiment. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

In the Saline Hypertonic in Preschoolers (SHIP) study, inhaled 7% hypertonic saline improved the lung clearance index in children aged 3-6 years with cystic fibrosis, but it remained unclear whether improvement is also seen in structural lung disease. We aimed to assess the effect of inhaled hypertonic saline on chest CT imaging in children aged 3-6 years with cystic fibrosis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

SHIP-CT showed that 48-week treatment with inhaled 7% hypertonic saline (HS) reduced airway abnormalities on chest CT using the manual PRAGMA-CF method relative to isotonic saline (IS) in children aged 3-6 years with cystic fibrosis (CF). An algorithm was developed and validated to automatically measure bronchus and artery (BA) dimensions of BA-pairs on chest CT. Aim of the study was to assess the effect of HS on bronchial wall thickening and bronchial widening using the BA-analysis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Early life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Aboriginal Australians have a fundamental human right to opportunities that lead to healthy and flourishing lives. While the impact of trauma on Aboriginal Australians is well-documented, a pervasive deficit narrative that focuses on problems and pathology persists in research and policy discourse. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

Inhalation of asbestos fibres produces persistent oxidative stress and inflammation in lungs. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• July 2015

Australia’s Childhood Immunisation Register (ACIR) is one of only a handful of national immunisation registers world-wide. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• April 2017

Parental investments in children are an important determinant of human capability formation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

The aim of this study was to investigate the link between vitamin D levels in the blood and short-sightedness in young adults. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

The long-term adherence to the dietary guidelines has not been evaluated against emergence of cardiometabolic risks in adolescents with increasing rates of... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015