There is a growing need for early biomarkers that may predict the development of atopic dermatitis (AD). As alterations in skin barrier may be a primary event in disease pathogenesis, epithelial cell (EC) cytokines expression patterns may be a potential biomarker in early life to target allergy preventive strategies towards "at-risk" infants. The aim of this longitudinal investigation was to examine from birth over the course of infancy levels of the EC cytokines: thymic stromal lymphopoietin (TSLP), interleukin (IL)-33, IL-25, and IL-17 in infants at high-risk of AD due to maternal atopy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

We argue that the success of planetary health solutions is predicated on a more sophisticated understanding of the psychology of prevention and intervention at all scales ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

Here, we explore the history of planetary health and describe its relevance to contemporary healthcare ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

This review covers basic aspects of histone modification and the role of posttranslational histone modifications in the development of allergic diseases ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Intergenerational trauma research typically focuses on parent survivors. No specific guidelines are available for conducting research with parent survivors despite potentially unique risks. To investigate research safety with parent survivors, we conducted an online survey of 38 researchers regarding experiences of parent survivors in their research, precautions taken, ethical review experiences, and researchers’ mental health during the project(s).  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

determining if regular consumption of egg protein from age 4 to 6 months reduces the risk of IgE mediated allergy in infants with genetic risk, without eczema. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017

Over the past decade, a growing number of studies have linked urban green space and aspects of biodiversity with emotional wellbeing. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• July 2017

Study the innate immune function in ulcerative colitis patients who fail to respond to anti-tumor necrosis factor therapy ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• November 2016

Mechanisms-including aerobiological and epigenetic-that might help explain some of the noted positive health outcomes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

To show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• February 2012

This study examined whether maternal and/or fetal folate status in pregnancy is associated with infant allergic outcomes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012